The Thirty-Fifth Anniversary of K+ Channels in O2 Sensing: What We Know and What We Don’t Know
Asuncion Rocher,
Philip I. Aaronson
Abstract:On the thirty-fifth anniversary of the first description of O2-sensitive K+ channels in the carotid body chemoreceptors O2 sensing remains a salient issue in the literature. Whereas much has been learned about this subject, important questions such as the identity of the specific K+ channel subtype(s) responsible for O2 sensing by chemoreceptors and the mechanism(s) by which their activities are altered by hypoxia have not yet been definitively answered. O2 sensing is a fundamental biological process necessary… Show more
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