The thiobarbituric acid test for lipid peroxidation: Structure of the adduct with malondialdehyde

Nair, Vasu; Turner, Gregory A.

doi:10.1007/bf02534475

Cited by 205 publications

(88 citation statements)

References 7 publications

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“…Polyunsaturated lipids are easily oxidized by reactive oxygen species resulting in a chain of reactions that has malondialdehyde as a major product [72]. APDT with S137 or NMBN but not with MB or TBO caused the peroxidation of arthroconidial lipids and consequently malondialdehyde production (see Fig.…”

Section: Discussionmentioning

confidence: 99%

In vitro susceptibilities of Neoscytalidium spp. sequence types to antifungal agents and antimicrobial photodynamic treatment with phenothiazinium photosensitizers

et al. 2018

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In vitro susceptibilities of Neoscytalidium spp. sequence types to antifungal agents and antimicrobial photodynamic treatment with phenothiazinium photosensitizers http://researchonline.ljmu.ac.uk/7434/ Article LJMU has developed LJMU Research Online for users to access the research output of the University more effectively. Copyright © and Moral Rights for the papers on this site are retained by the individual authors and/or other copyright owners. Users may download and/or print one copy of any article(s) in LJMU Research Online to facilitate their private study or for non-commercial research. You may not engage in further distribution of the material or use it for any profit-making activities or any commercial gain.The version presented here may differ from the published version or from the version of the record. Please see the repository URL above for details on accessing the published version and note that access may require a subscription.

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Section: Discussionmentioning

confidence: 99%

In vitro susceptibilities of Neoscytalidium spp. sequence types to antifungal agents and antimicrobial photodynamic treatment with phenothiazinium photosensitizers

et al. 2018

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“…Zinc concentrations in serum samples were measured using atomic absorption spectrophotometer (Shimadzu AA-6800). Serum levels of malondialdehyde (MDA), a marker of lipid peroxidation, were evaluated as thiobarbituric acid reactive substances (TBARS) by the method of Nair and Turner (36). The activities of erythrocyte glutathione peroxidase (GSH-Px), superoxide dismutase (SOD), and catalase (CAT) were determined according to our previously described procedures (37).…”

Section: Biochemical Assays and Analysismentioning

confidence: 99%

Comparative Study of Antidiabetic Activity and Oxidative Stress Induced by Zinc Oxide Nanoparticles and Zinc Sulfate in Diabetic Rats

Nazarizadeh

Asri-Rezaie

2015

AAPS PharmSciTech

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Abstract. In the current study, antidiabetic activity and toxic effects of zinc oxide nanoparticles (ZnO) were investigated in diabetic rats compared to zinc sulfate (ZnSO 4 ) with particular emphasis on oxidative stress parameters. One hundred and twenty male Wistar rats were divided into two healthy and diabetic groups, randomly. Each major group was further subdivided into five subgroups and then orally supplemented with various doses of ZnO (1, 3, and 10 mg/kg) and ZnSO 4 (30 mg/kg) for 56 consecutive days. ZnO showed greater antidiabetic activity compared to ZnSO 4 evidenced by improved glucose disposal, insulin levels, and zinc status. The altered activities of erythrocyte antioxidant enzymes as well as raised levels of lipid peroxidation and a marked reduction of total antioxidant capacity were observed in rats receiving ZnO. ZnO nanoparticles acted as a potent antidiabetic agent, however, severely elicited oxidative stress particularly at higher doses.

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“…Plasma NO (nitrate + nitrite) was measured according to Behrooj et al (2012). Plasma MDA concentration was determined as an index of lipid peroxidation by the TBA method (Nair and Turner, 1984).…”

Section: Acta Veterinaria Hungarica 62 2014mentioning

confidence: 99%

L-carnitine supplementation decreases lipid peroxidation and improves cardiopulmonary function in broiler chickens reared at high altitude

Khajali

2014

Acta Veterinaria Hungarica

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An experiment was carried out to examine the effects of L-carnitine supplementation on growth performance and cardiopulmonary function of broiler chickens reared at high altitude (2100 m above sea level). A total of 96 day-old male chicks (Cobb 500) were randomly assigned into two dietary treatments containing 0 (control group) and 200 mg/kg L-carnitine. The experimental diets were fed for a period of 42 days consisting of the starting (days 1 to 21) and growing periods (days 21 to 42). Nutrient requirements of chickens met the NRC (1994) recommendations. The results showed that dietary L-carnitine had no significant influence on body weight gain, feed intake and feed conversion ratio. L-carnitine reduced plasma concentration of malondialdehyde, packed cell volume (PCV) and abdominal fat deposition compared to the control (P < 0.05). A significant (P < 0.05) decrease was observed in the right to total ventricular weight ratio (RV:TV) in birds receiving L-carnitine when compared to the control. Supplementation of L-carnitine increased plasma nitric oxide and immune responsiveness, which manifested in an increased toe-web thickness index measured at 24 h following the injection of phytohaemagglutinin P. In conclusion, supplementation of Lcarnitine had beneficial effects on preventing lipid peroxidation and pulmonary hypertension in broiler chickens raised at high altitude.

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The thiobarbituric acid test for lipid peroxidation: Structure of the adduct with malondialdehyde

Abstract: The complete structure of the red crystalline 2:1 adduct from thiobarbituric acid and malondialdehyde has been unambiguously determined by FTIR and high-field 1 H and 13C NMR studies.

Cited by 205 publications

References 7 publications

In vitro susceptibilities of Neoscytalidium spp. sequence types to antifungal agents and antimicrobial photodynamic treatment with phenothiazinium photosensitizers

In vitro susceptibilities of Neoscytalidium spp. sequence types to antifungal agents and antimicrobial photodynamic treatment with phenothiazinium photosensitizers

Comparative Study of Antidiabetic Activity and Oxidative Stress Induced by Zinc Oxide Nanoparticles and Zinc Sulfate in Diabetic Rats

L-carnitine supplementation decreases lipid peroxidation and improves cardiopulmonary function in broiler chickens reared at high altitude

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