The thick and thin of the central corneal thickness in glaucoma

Belovay, Graham W.; Goldberg, Ivan

doi:10.1038/s41433-018-0033-3

Cited by 57 publications

(52 citation statements)

References 111 publications

(136 reference statements)

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…Corneal thickness is associated with IOP. As for IOP measurement, thicker cornea results in higher IOP than thinner cornea [19,20]. In eyes with thicker cornea, postoperative IOP after trabeculectomy might be overestimated compared to the actual IOP.…”

Section: Discussionmentioning

confidence: 99%

Prospective cohort study of risk factors for choroidal detachment after trabeculectomy

et al. 2020

View full text Add to dashboard Cite

Purpose To investigate risk factors for choroidal detachment after trabeculectomy. Methods We prospectively evaluated 97 patients with open-angle glaucoma who underwent primary trabeculectomy to investigate risk factors for choroidal detachment after trabeculectomy. The primary outcome measure was risk factors for the occurrence and severity of choroidal detachment after trabeculectomy. Choroidal detachment severity was quantified as the number of fundus quadrants with choroidal detachment. Results Sixteen patients (16.5%) had choroidal detachment. Mean period between surgery and occurrence of choroidal detachment was 7.9 ± 5.7 days. Mean intraocular pressure (IOP) on the first day of choroidal detachment was 6.1 ± 3.0 mm Hg. Multivariable analyses revealed that the exfoliation glaucoma, greater DIOP between preoperative and lowest postoperative IOPs, and thicker cornea were associated with choroidal detachment (P = 0.022, P = 0.002, and P = 0.013, respectively). These factors were also associated with the severity of choroidal detachment (exfoliation glaucoma; P = 0.013, greater DIOP; P \ 0.001, and thicker cornea; P = 0.006).Conclusions Exfoliation glaucoma, more IOP reduction, and thicker cornea are associated with the occurrence and severity of choroidal detachment after trabeculectomy.

show abstract

Section: Discussionmentioning

confidence: 99%

Prospective cohort study of risk factors for choroidal detachment after trabeculectomy

et al. 2020

View full text Add to dashboard Cite

show abstract

“…A worldwide meta-analysis found that the average CCT for normal eyes derived from various racial groups, regardless of the device used, was 544 μm [ 21 ], a value that is thinner than that for the Jordanian population we studied (550 μm). Comparing CCT values of our Jordanian population with Caucasian ethnicity, the most represented ethnicity in ethnicity-comparing studies [ 22 ], Caucasian ethnicity mean CCT was similar to Jordanian’s (550 ± 30.5 μm) [ 23 ]. On the other hand, African ethnicity has a lower CCT than that for Jordanians (514.77 ± 31.86) [ 23 ].…”

Section: Discussionmentioning

confidence: 99%

“…On the other hand, African ethnicity has a lower CCT than that for Jordanians (514.77 ± 31.86) [ 23 ]. It should be noted that the technique used to measure CCT can affect the results [ 24 ], and although the results from commonly used devices mostly correlate, the direct comparison between them might not be accurate [ 22 ], so that we will only include studies that used similar techniques for direct value comparison purposes. Regarding CCT difference between different glaucoma types, only PACG eyes have thinner corneas compared to POAG, PXFG, and control eyes, This comes in accordance with what a recent study suggested, where no difference in corneal thickness between POAG, PXFG, and control eyes was found [ 25 ].…”

Section: Discussionmentioning

confidence: 99%

Central corneal thickness in a Jordanian population and its association with different types of Glaucoma: cross-sectional study

et al. 2018

View full text Add to dashboard Cite

BackgroundCentral corneal thickness (CCT) has long been implicated to affect glaucoma predisposition. Several reports have identified that thinner CCT is a risk factor for open-angle glaucoma, and that CCT can be very variable between different ethnic groups. In this study, we aim to identify the relation between CCT and different glaucoma parameters in different types of glaucoma in an Arabian ethnicity.MethodsWe classified our participants into four main groups: primary open-angle glaucoma (POAG), primary angle-closure glaucoma (PACG), pseudoexfoliative glaucoma (PXFG), and a control group. We obtained demographics, intraocular pressure (IOP), cup to disc ratio (CDR), visual field mean deviation (MD) and pattern standard deviation (PSD), CCT, and retinal nerve fiber layer (RNFL) thickness for each participant.ResultsWe included A total of 119 eyes with glaucoma, including POAG (54 eyes), PXFG (31 eyes) and PACG (34 eyes), we also included 57 control eyes. We found that PACG eyes have the thinnest CCT. Mean measurements of CCT for our groups were: 538.31 μm (SD = 36.30) in eyes with POAG, 544.45 μm (SD = 28.57) in eyes with PXFG, 506.91 μm (SD = 34.55) in eyes with PACG and 549.63 μm (SD = 42.9) in the control group. We found that CCT is significantly correlated with CDR (p = 0.012, r = − 0.231), MD (p < 0.001, r = 0.327),and RNFL thickness (p = .007, r = .283).ConclusionIn Arabian ethnicity, PACG patients have the thinnest CCT compared to other types of glaucoma, namely POAG and PXFG. We demonstrated that glaucomatous eyes with thinner corneas will probably have more advanced glaucomatous optic neuropathy. Our results emphasize the importance of taking ethnicity into account upon glaucoma management.

show abstract

“…In fact, important correlations between corneal pachymetry and glaucoma have emerged unequivocally, due to the diffusion of refractive surgery and the related pre-op tests. Considering that the CCT in normal conditions is just over half a millimeter (540 ± micron), patients with thin cornea have a higher risk of development and progression of glaucomatous damage, while those with thick cornea are more protected from glaucomatous risk ( Figure 6) (Gaspar et al, 2017;Belovay and Goldberg, 2018). However, it is important to remember that measurement of IOP by standard techniques is lower than the real value in patients with thin cornea and higher in those with thick cornea.…”

Section: Glaucoma Diagnosismentioning

confidence: 99%

The Hub-and-Spoke Management of Glaucoma

Nuzzi

2020

Front. Neurosci.

View full text Add to dashboard Cite

Glaucoma is an extremely significant public health issue, since it is the most common cause of irreversible blindness worldwide, nevertheless it is still widely undiagnosed because of its devious nature. Glaucoma diagnosis criteria are well-defined and have to be strictly observed and recognized: the earlier the disease is diagnosed, the earlier the patient can undergo the most suitable treatment, the better can be the prognosis. The three levels of prevention are essential in the approach to the disease and its pathophysiological features make it eligible for screening. This review provides an overview of the current state of the art in glaucoma management, starting from its prevention and coming to the hub-and-spoke organization. This model applied to glaucoma aims to direct patients toward professional and not professional figures who may guide them in integrated care pathway. This path should be designed in accordance with best practice to coordinate glaucoma prevention, diagnosis, treatment and follow up with the best cost-benefit ratio, protecting both the interests of the patient and of the society.

show abstract

The thick and thin of the central corneal thickness in glaucoma

Cited by 57 publications

References 111 publications

Prospective cohort study of risk factors for choroidal detachment after trabeculectomy

Prospective cohort study of risk factors for choroidal detachment after trabeculectomy

Central corneal thickness in a Jordanian population and its association with different types of Glaucoma: cross-sectional study

The Hub-and-Spoke Management of Glaucoma

Contact Info

Product

Resources

About