Abstract:Background: Chemotherapy-induced peripheral neuropathy (CIPN) is common
in pateints undergoing chemotherapy. Hexuetongbi (HXTB), a TCM, could
treat CIPN. Objective: This study investigates HXTB in treating CIPN and
the underlying mechanism in an oxaliplatin-induced rat model (model).
Methods: The rat model was developed by intraperitoneal injection of
oxaliplatin for four weeks. The HXTB was investigated on the behavior of
rats. Network analysis, TCMSP, and GeneCards were used to identify CIPN
targets and HXTB… Show more
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