The Therapeutic Effects of Epigallocatechin-3-gallate and Rutin, either Alone or in Combination with Low-dose radiation, against Testicular Injury Evoked by Nicotine in Rats
Abstract:G ROWING evidence suggests that nicotine, the addictive component of cigarettes, plays a direct role in testicular injury and infertility. The present study was intended to investigate the therapeutic effect of epigallocatechin-3-gallate (EGCG) and rutin (RUT), either alone or in combination with a low-dose radiation (LDR), against testicular injury evoked by nicotine in rats. For the induction of testicular injury, nicotine (1mg/kg) was administered orally for 30 days. Following that, rats were administered E… Show more
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