The Test-retest Reliability And Exercise-driven Changes Of UCH-L1 In Healthy, Recreationally Active College Students

Cabell, Grant H.; Teel, Elizabeth; Hanson, Erik D.; Mihalik, Jason P.; Guskiewicz, Kevin M.

doi:10.1249/01.mss.0000538747.81701.2e

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2021

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“…Compared with controls, blood UCH-L1 and tau levels are typically higher among recreational athletes, even in the absence of a TBI or concussion. 28 , 29 Serum NfL level has been reported to be a prognostic factor associated with negative outcomes after diagnosed TBI. 30 , 31 Overall, the concentration range of UCH-L1, tau, or NfL may be higher in military and law enforcement personnel even at rest owing to physical training.…”

Section: Discussionmentioning

confidence: 99%

“…Elevated UCH-L1 level has been reported hours after LLOP, possibly owing to release from muscle in addition to neuronal tissues. Compared with controls, blood UCH-L1 and tau levels are typically higher among recreational athletes, even in the absence of a TBI or concussion . Serum NfL level has been reported to be a prognostic factor associated with negative outcomes after diagnosed TBI .…”

Section: Discussionmentioning

confidence: 99%

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