The Temporal Lobe as a Symptomatogenic Zone in Medial Parietal Lobe Epilepsy

Jaafar, Nadim; Bhatt, Amar B.; Eid, Alexandra; Koubeissi, Mohamad Z.

doi:10.3389/fneur.2022.804128

Cited by 3 publications

(2 citation statements)

References 56 publications

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“…Given the strong recommendation of precuneus sampling in patients with temporal lobe epilepsy symptoms (Jaafar et al, 2022), this pathway should be considered for sampling in addition to pulvinar pathways during the investigation of epileptogenic networks in patients with mesial temporal lobe, occipital and/or motor symptoms.…”

Section: Discussionmentioning

confidence: 99%

“…Accordingly, the fiber tract connecting the POS2 and TP may represent a structural substrate for occipital, motor extra‐thalamic, and mesial temporal lobe seizures. Given the strong recommendation of precuneus sampling in patients with temporal lobe epilepsy symptoms (Jaafar et al, 2022 ), this pathway should be considered for sampling in addition to pulvinar pathways during the investigation of epileptogenic networks in patients with mesial temporal lobe, occipital and/or motor symptoms. Future studies focused on patients suffering from neurological and psychiatric conditions may uncover their underlying pathophysiology and determine the role of connectivity between POS2 and TP in these disorders.…”

Section: Discussionmentioning

confidence: 99%

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Unveiling the axonal connectivity between the precuneus and temporal pole: Structural evidence from the cingulum pathways

Skandalakis,

Linn,

Yeh

et al. 2024

Human Brain Mapping

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Neuroimaging studies have consistently demonstrated concurrent activation of the human precuneus and temporal pole (TP), both during resting‐state conditions and various higher‐order cognitive functions. However, the precise underlying structural connectivity between these brain regions remains uncertain despite significant advancements in neuroscience research. In this study, we investigated the connectivity of the precuneus and TP by employing parcellation‐based fiber micro‐dissections in human brains and fiber tractography techniques in a sample of 1065 human subjects and a sample of 41 rhesus macaques. Our results demonstrate the connectivity between the posterior precuneus area POS2 and the areas 35, 36, and TG of the TP via the fifth subcomponent of the cingulum (CB‐V) also known as parahippocampal cingulum. This finding contributes to our understanding of the connections within the posteromedial cortices, facilitating a more comprehensive integration of anatomy and function in both normal and pathological brain processes.Practitioner PointsOur investigation delves into the intricate architecture and connectivity patterns of subregions within the precuneus and temporal pole, filling a crucial gap in our knowledge. We revealed a direct axonal connection between the posterior precuneus (POS2) and specific areas (35, 35, and TG) of the temporal pole. The direct connections are part of the CB‐V pathway and exhibit a significant association with the cingulum, SRF, forceps major, and ILF. Population‐based human tractography and rhesus macaque fiber tractography showed consistent results that support micro‐dissection outcomes.

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Section: Discussionmentioning

confidence: 99%

Section: Discussionmentioning

confidence: 99%

Unveiling the axonal connectivity between the precuneus and temporal pole: Structural evidence from the cingulum pathways

Skandalakis,

Linn,

Yeh

et al. 2024

Human Brain Mapping

View full text Add to dashboard Cite

show abstract

Posterior cingulate epilepsy: Seizure semiology and intracranial electrical stimulation using SEEG

Yan,

Yang,

Wang

et al. 2024

Seizure: European Journal of Epilepsy

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Somatosomesthetic hallucinations in parietal lobe seizures: A case report

Assis

Antunes

Santos

et al. 2022

Int J Case Rep Images

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Introduction: A transient occurrence of signs and symptoms brought on by excessive abnormal neuronal or synchronous activity in the brain is known as an epileptic seizure. By way of onset, seizures can be classified as focal, generalized, unknown, or unclassifiable. An underlying structural abnormality can cause focal seizures in the brain. Among these, the temporal lobe is the most prevalent, but there may be alterations in the frontal, occipital, and parietal lobes. The objective of this case report is to contribute to the knowledge of the multiple symptoms of patients with parietal lobe seizures. Case Report: The report is about parietal aura, diagnosed in the patient J.F.R., a 45-year-old male, and reported his first seizure in 2017. The patient said the increasing onset of the condition leads to significant body image disorders (the representation of the child during eye contact is similar to that of a monster). A limb or a body side may also appear heavier, more significant, absent, or separate from the rest of the body. The postictal period was slow, and full consciousness and correct body image emerged insidiously. Conclusion: In the evaluation, it is essential to value not only the main complaint but also the entire psychic context, cognitive function, and interpersonal and social relationships since these aspects can affect the quality of life of these patients and their integration into the social environment.

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The Temporal Lobe as a Symptomatogenic Zone in Medial Parietal Lobe Epilepsy

Cited by 3 publications

References 56 publications

Unveiling the axonal connectivity between the precuneus and temporal pole: Structural evidence from the cingulum pathways

Unveiling the axonal connectivity between the precuneus and temporal pole: Structural evidence from the cingulum pathways

Posterior cingulate epilepsy: Seizure semiology and intracranial electrical stimulation using SEEG

Somatosomesthetic hallucinations in parietal lobe seizures: A case report

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