The Tecumseh Study of Respiratory Illness

Monto, Arnold S.; Cavallaro, Joseph J.

doi:10.1093/oxfordjournals.aje.a121321

Cited by 139 publications

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“…Adults in the United States suffer an average of two to four “colds” per year, with more frequent occurrence during the winter months. 11,12 ARI in military camps has been shown to follow these patterns as well. 13,14 …”

Section: Introductionmentioning

confidence: 80%

Association Between Barracks Type and Acute Respiratory Infection in a Gender Integrated Army Basic Combat Training Population

et al. 2011

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Background Acute respiratory infections (ARIs) are the leading cause of acute morbidity and lost work time in the United States. Few studies have looked at building design and transmission of ARIs. Objectives This study explores the association of ventilation design, room occupancy numbers, and training week with ARI rates in Army Basic Combat Training barracks. Methods This observational study captured the overall incidence of ARI in a cohort of 16,258 individuals attending basic combat training at Fort Jackson, South Carolina. Results ARI risk was higher among trainees living in the 60-person room barracks compared with those living in 8-person rooms, which increased rapidly for the first few weeks of training and then declined to baseline. Conclusions Findings support direct contact as primary ARI transmission mode in this study population based on observed lower ARI risk in smaller room barracks and similar risk in large room barracks despite heating, ventilation, and air conditioning system variability.

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Section: Introductionmentioning

confidence: 80%

Association Between Barracks Type and Acute Respiratory Infection in a Gender Integrated Army Basic Combat Training Population

et al. 2011

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“…Indeed, family size and composition have been associated with both social contact frequency and the risk of infection with influenza and other respiratory pathogens [7], [8], [9].…”

Section: Introductionmentioning

confidence: 99%

Social Contact Patterns in Vietnam and Implications for the Control of Infectious Diseases

et al. 2011

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BackgroundThe spread of infectious diseases from person to person is determined by the frequency and nature of contacts between infected and susceptible members of the population. Although there is a long history of using mathematical models to understand these transmission dynamics, there are still remarkably little empirical data on contact behaviors with which to parameterize these models. Even starker is the almost complete absence of data from developing countries. We sought to address this knowledge gap by conducting a household based social contact diary in rural Vietnam.Methods and FindingsA diary based survey of social contact patterns was conducted in a household-structured community cohort in North Vietnam in 2007. We used generalized estimating equations to model the number of contacts while taking into account the household sampling design, and used weighting to balance the household size and age distribution towards the Vietnamese population. We recorded 6675 contacts from 865 participants in 264 different households and found that mixing patterns were assortative by age but were more homogenous than observed in a recent European study. We also observed that physical contacts were more concentrated in the home setting in Vietnam than in Europe but the overall level of physical contact was lower. A model of individual versus household vaccination strategies revealed no difference between strategies in the impact on R 0.Conclusions and SignificanceThis work is the first to estimate contact patterns relevant to the spread of infections transmitted from person to person by non-sexual routes in a developing country setting. The results show interesting similarities and differences from European data and demonstrate the importance of context specific data.

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“…A prerequisite of public health planning to reduce global disease burden from ARI is to examine data on its epidemiology in order to better define environmental factors as well as target populations for preventive interventions [4]. Respiratory viruses are predominant causes of ARIs, and the epidemiology of acute viral respiratory illnesses in developed countries with temperate climates has been well-characterized [5][6][7]. In countries such as the United States, children have been shown to carry a large burden of viral respiratory diseases [5].…”

Section: Introductionmentioning

confidence: 99%

Sentinel Surveillance of Influenza-Like Illness in Two Hospitals in Maracay, Venezuela: 2006–2010

et al. 2012

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BackgroundLimited information exists on the epidemiology of acute febrile respiratory illnesses in tropical South American countries such as Venezuela. The objective of the present study was to examine the epidemiology of influenza-like illness (ILI) in two hospitals in Maracay, Venezuela.Methodology/Principal FindingsWe performed a prospective surveillance study of persons with ILI who presented for care at two hospitals in Maracay, Venezuela, from October 2006 to December 2010. A respiratory specimen and clinical information were obtained from each participant. Viral isolation and identification with immunofluorescent antibodies and molecular methods were employed to detect respiratory viruses such as adenovirus, influenza A and B, parainfluenza, and respiratory sincytial virus, among others. There were 916 participants in the study (median age: 17 years; range: 1 month – 86 years). Viruses were identified in 143 (15.6%) subjects, and one participant was found to have a co-infection with more than one virus. Influenza viruses, including pandemic H1N1 2009, were the most frequently detected pathogens, accounting for 67.4% (97/144) of the viruses detected. Adenovirus (15/144), parainfluenza virus (13/144), and respiratory syncytial virus (11/144) were also important causes of ILI in this study. Pandemic H1N1 2009 virus became the most commonly isolated influenza virus during its initial appearance in 2009. Two waves of the pandemic were observed: the first which peaked in August 2009 and the second - higher than the preceding - that peaked in October 2009. In 2010, influenza A/H3N2 re-emerged as the most predominant respiratory virus detected.Conclusions/SignificanceInfluenza viruses were the most commonly detected viral organisms among patients with acute febrile respiratory illnesses presenting at two hospitals in Maracay, Venezuela. Pandemic H1N1 2009 influenza virus did not completely replace other circulating influenza viruses during its initial appearance in 2009. Seasonal influenza A/H3N2 was the most common influenza virus in the post-pandemic phase.

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The Tecumseh Study of Respiratory Illness

Cited by 139 publications

References 0 publications

Association Between Barracks Type and Acute Respiratory Infection in a Gender Integrated Army Basic Combat Training Population

Association Between Barracks Type and Acute Respiratory Infection in a Gender Integrated Army Basic Combat Training Population

Social Contact Patterns in Vietnam and Implications for the Control of Infectious Diseases

Sentinel Surveillance of Influenza-Like Illness in Two Hospitals in Maracay, Venezuela: 2006–2010

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