The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties

Gębarowski, Tomasz; Jęśkowiak, Izabela; Janeczek, Maciej; Żuk, Magdalena; Dobosz, Agnieszka; Wiatrak, Benita

doi:10.3390/ma14247736

Cited by 2 publications

(2 citation statements)

References 28 publications

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“…More recent research studies have carefully evaluated the efficacy of linen dressings to accelerate the healing process. Generally, the studies have proven the efficacy of using linen or flax oil to promote wound healing [ 95 , 96 , 97 , 98 , 99 , 100 , 101 ]. There exist some conflicting studies that have not shown much beneficial effect [ 102 , 103 ] and a concern of specific preparations of linen that may induce dermal irritation [ 99 ].…”

Section: Wound Healingmentioning

confidence: 99%

“…However, the majority of evidence would support the continued use of linen in promoting wound healing. The mechanisms by which flax fibres induce a protective action include an inhibition of skin cell apoptosis, promotion of skin cell growth [ 96 ], inhibition of inflammation [ 95 , 98 ], increased collagen synthesis and fibroblast proliferation [ 98 ], and protection against oxidative damage [ 95 ]. Combinations of flax extracts in the fibres with additional complementary wound healing elements appear to accelerate the wound healing process even further [ 102 , 104 , 105 ].…”

Section: Wound Healingmentioning

confidence: 99%

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Physiological and Pathological Considerations for the Use of Flaxseed as a Therapeutic Dietary Strategy

Hirst,

Dibrov,

Hirst

et al. 2023

Rev. Cardiovasc. Med.

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The inclusion of flaxseed in the diet may have a great number of potential benefits for the well-being of both healthy individuals and those challenged by disease conditions as well. With an increase in the number and quality of studies focused on the physiological and pathophysiological effects of dietary flaxseed, our knowledge concerning the rationale for the inclusion of flaxseed in our diet has become more convincing and stronger. The purpose of this review is threefold. First, the review will comprehensively document the evidence supporting the value of dietary flaxseed to improve bodily health in both normal and disease conditions. Second, this review will identify the mechanisms of action responsible for these effects. Finally, this article will review practical aspects relevant to the inclusion of flaxseed in the diet. Briefly, supplementing the diet with flaxseed has beneficial effects on the treatment and/or prevention of different kinds of cardiovascular disease (hypertension, ischemic heart disease, myocardial infarcts, atherosclerosis), non-alcoholic fatty liver disease, breast cancer, bone strength, menopause, diabetes, and wound healing. Although some controversy exists on the component within flaxseed that provides these beneficial actions, it is likely that the rich content of the omega-3 fatty acid, alpha linolenic acid, is primarily responsible for the majority of these biological effects. It is concluded that the constantly expanding evidence in support of the inclusion of flaxseed in our daily diet to provide significant health benefits strongly encourages the initiation of additional work on dietary flaxseed in order to both confirm past findings as well as to further advance our knowledge regarding the important biological actions of dietary flaxseed.

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Section: Wound Healingmentioning

confidence: 99%

Section: Wound Healingmentioning

confidence: 99%

Physiological and Pathological Considerations for the Use of Flaxseed as a Therapeutic Dietary Strategy

Hirst,

Dibrov,

Hirst

et al. 2023

Rev. Cardiovasc. Med.

View full text Add to dashboard Cite

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Investigation of the Properties of Linen Fibers and Dressings

Gębarowski

Jęśkowiak

Wiatrak

2022

IJMS

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In antiquity, flax was used as a dressing for healing wounds. Currently, work is underway on the genetic modification of flax fibers to improve their properties. Genetic modifications have resulted in an increased content of antioxidants and more favorable mechanical properties. The works published so far have presented independent tests of fibers and dressings after appropriate technological treatments in cell cultures. This study aimed to compare the properties of the fibers and the dressing produced in cell cultures—hamster fibroblasts—V79. The research material was traditional NIKE fibers; genetically modified M, B, and MB fibers; and linen dressings obtained from these fibers. The extract from 48-h incubation of 40 mg of fiber in the culture medium, which was desolved into 10, 20, and 30 mg, was administered to the cell culture. On the other hand, a linen dressing was placed on cells with an area of 0.5 cm2, 1 cm2, 1.5 cm2, and 2 cm2. Cells with fiber or dressing were incubated for 48 h, and then, biological tests were performed, including cell viability (in propidium iodide staining), cell proliferation (in the SRB assay), evaluation of the intracellular free radical level (in the DCF-DA assay), genotoxicity (in the comet assay), assessment of the apoptotic and necrotic cells (in staining anexin-V and iodide propidium), the course of the cell cycle, and the scratch test. The correlation between apoptosis and genotoxicity and the levels of free radicals and genotoxicity were determined for the tested linen fibers and fabrics. The tests presented that the fibers are characterized by the ability to eliminate damaged cells in the elimination phase. However, the obtained fabrics gain different properties during the technological processing of the fibers into linen dressings. Linen fabrics have better regenerative properties for cells than fibers. The linseed dressing made of MB fiber has the most favorable regenerative properties.

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The Technological Process of Obtaining New Linen Dressings Did Not Cause the Loss of Their Wound-Healing Properties

Cited by 2 publications

References 28 publications

Physiological and Pathological Considerations for the Use of Flaxseed as a Therapeutic Dietary Strategy

Physiological and Pathological Considerations for the Use of Flaxseed as a Therapeutic Dietary Strategy

Investigation of the Properties of Linen Fibers and Dressings

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