The T-ACE questions: Practical prenatal detection of risk-drinking

Sokol, Robert J.; Martier, Susan S.; Ager, Joel W.

doi:10.1016/0002-9378(89)90302-5

Cited by 424 publications

(310 citation statements)

References 14 publications

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“…22 When answering the questionnaire, whoever reaches a score of ≥ 2 is considered a positive case, i.e., is identified as an alcohol consumer. 20,22 The results were analyzed by distinguishing two groups of participants according to the T-ACE score: T-ACE negative (T-ACE score <2) and T-ACE positive (T-ACE score ≥ 2).…”

Section: Methodsmentioning

confidence: 99%

“…11,13 In Brazil, studies carried out using different methodologies estimate the frequency of alcohol consumption around to be approximately 10 to 40% of pregnant women. [14][15][16][17][18][19] T-ACE (Tolerance, Annoyed, Cut Down, and Eye-opener) was the first validated alcohol consumption screening questionnaire for use in obstetrical and gynecological practices, 20 and is routinely used in various services proving to be efficient in detecting pregnant women who consume alcohol. 1,21,22 A Brazilian Portuguese version of T-ACE, translated and adapted from the original questionnaire of Sokol et al, 20 was validated by Fabbri et al 22 in 2001. .…”

Section: Introductionmentioning

confidence: 99%

“…[14][15][16][17][18][19] T-ACE (Tolerance, Annoyed, Cut Down, and Eye-opener) was the first validated alcohol consumption screening questionnaire for use in obstetrical and gynecological practices, 20 and is routinely used in various services proving to be efficient in detecting pregnant women who consume alcohol. 1,21,22 A Brazilian Portuguese version of T-ACE, translated and adapted from the original questionnaire of Sokol et al, 20 was validated by Fabbri et al 22 in 2001. . When compared to ICD-10 criteria for alcohol abuse identification and alcohol dependence syndrome, the Brazilian version of the T-ACE questionnaire showed sensitivity and specificity coefficients of 100% and 85.6% respectively, indicating good performance as a screening tool for problems related to alcohol consumption during pregnancy.…”

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

Prevalence and factors associated with alcohol consumption during pregnancy

Baptista

Rocha

Martinelli

et al. 2017

Rev. Bras. Saude Mater. Infant.

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Section: Methodsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

Prevalence and factors associated with alcohol consumption during pregnancy

Baptista

Rocha

Martinelli

et al. 2017

Rev. Bras. Saude Mater. Infant.

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“…These interviews have been designed and validated to limit denial and elicit sensitive drug and alcohol-use information from pregnant women. 33,37 The structured interview included the full-scale Michigan Alcoholism Screening Test 38 and T-ACE (Tolerance, Angry or Annoyance, Cut down or quit, eye opener) scales 39 to identify risk drinkers. 32 Socioeconomic status (SES) was measured by using a modified Hollingshead 2-factor index (occupation and education) of social position.…”

Section: Participantsmentioning

confidence: 99%

Effects of Alcohol Intake During Pregnancy on Docosahexaenoic Acid and Arachidonic Acid in Umbilical Cord Vessels of Black Women

Beblo

Murthy

Janisse³

et al. 2005

Pediatrics

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ABSTRACT. Objective. Alcohol influences the intake and metabolism of several nutrients including longchain polyunsaturated fatty acids (LC-PUFAs). The LCPUFAs docosahexaenoic acid (DHA) and arachidonic acid (AA) are particularly crucial for intrauterine growth and brain development. We hypothesized that alcohol consumption adversely affects LC-PUFA levels in pregnant women and their newborn infants.Methods. Pregnant black women (N ‫؍‬ 208) presenting at a core city antenatal clinic were screened and recruited. Shortly before delivery, maternal plasma was collected. After delivery, umbilical arteries and veins were dissected from the cords, total lipids were extracted from the vessel tissues and maternal plasma, and fatty acid levels were assayed by gas chromatography. For statistical analysis, subjects were categorized according to absolute alcohol intake per day (AAD) and absolute alcohol intake per drinking day (AADD) around the time of conception, with smoking and other potential confounders included in the analyses.Results. Significant differences in fatty acid composition of total lipid extracts were detected in umbilical cord vessels among the AADD groups: abstainers (AADD ‫؍‬ 0), moderate drinkers (AADD < 130 g), and heavy drinkers (AADD > 130 g). DHA and AA content in the arterial umbilical vessel wall was ϳ14% and ϳ10% higher in the moderate (n ‫؍‬ 127) and heavy (n ‫؍‬ 32) alcohol groups, respectively, than in abstainers (n ‫؍‬ 49). A small, nonsignificant increase (ϳ3%) was seen in the umbilical vein for AA but not for DHA. Alcohol intake was positively correlated to both DHA and AA concentrations in the arterial vessel wall but to neither in the venous wall nor maternal plasma. Maternal plasma DHA was positively correlated with both umbilical arteries and vein DHA, but there were no significant correlations for AA between maternal plasma and either umbilical vessel.Conclusions. Our findings indicate that alcohol intake during pregnancy is associated with altered DHA and AA status in fetal tissues. Although differences may be due to either metabolism and/or distribution, it is most likely a result of a direct influence of alcohol on fetal metabolism. Pediatrics 2005;115:e194-e203. URL: www.pediatrics.org/cgi

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“…The T-ACE (Tolerance, Annoyed by criticism, Cut down, Eye-opener) 14 and the TWEAK (Tolerance, Worry about drinking, Eye-opener, Amnesia, K/Cut down) [15][16][17] have been validated as reliable screening instruments for obstetrical practice, but, again, heavy drinkers are the primary targets of these two instruments, and they do not identify more moderate or light drinkers or users of illicit drugs.…”

Section: Introductionmentioning

confidence: 99%

et al. 2005

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Determine the prevalence of substance use among pregnant women in five diverse communities utilizing the 4P's Plus r screen for alcohol, tobacco, and other drug use. STUDY DESIGN:Pregnant women enrolled in prenatal care clinics in five communities were screened for substance use with the 4P's Plus r . Those women with a positive screen underwent an assessment for substance use through a follow-up structured clinical interview conducted at the same prenatal visit. RESULTS:Among 7818 women in five communities, 2555 (32.7%) had a positive screen for substance use in pregnancy. Four of the communities conducted a follow-up assessment on all women with a positive screen (n ¼ 1548). Among these women, 717 (15% of the total population) had continued use after learning of the pregnancy. Overall, 21% of the pregnant women used alcohol prior to recognition of the pregnancy, and 11% continued use after knowledge of the pregnancy. Among the 512 women who continued to use alcohol, 2% were drinking daily, 7% were drinking 3 to 6 days per week, 27% were drinking 1 to 2 days per week, and 63% were drinking less than 1 day per week. The rates of marijuana use and other illicit drug use among the women were 7 and 2%, respectively, prior to knowledge of pregnancy and dropped to 3 and 1% after learning of the pregnancy. CONCLUSION:The 4P's Plus r identifies not only those pregnant women whose drinking or drug use is at a high enough level to impair daily functioning, but provides an opportunity for early intervention for the much larger group of women whose pregnancies are at risk from relatively small amounts of substance use.

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The T-ACE questions: Practical prenatal detection of risk-drinking

Cited by 424 publications

References 14 publications

Prevalence and factors associated with alcohol consumption during pregnancy

Prevalence and factors associated with alcohol consumption during pregnancy

Effects of Alcohol Intake During Pregnancy on Docosahexaenoic Acid and Arachidonic Acid in Umbilical Cord Vessels of Black Women

The 4P's Plus© Screen for Substance Use in Pregnancy: Clinical Application and Outcomes

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