The System Used in Belgium to Monitor Erwinia Amylovora (Burrill) Winslow Et Al.

Geenen, Jarret; Vantomme, R.; Veldeman, R.

doi:10.17660/actahortic.1981.117.19

Cited by 4 publications

(2 citation statements)

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“…However, we and several other groups have demonstrated that thymic epithelial cells (TECs) from different species constitute a site for promiscuous transcription of a great number of genes belonging to neuroendocrine families, such as the neurohypophysial family, 3 tachykinins, 4 neurotensins 5 and the insulin family. 6,7 The nature of neuroendocrine self was then defined as follows: 7…”

Section: Thymus Physiology and The Nature Of 'Neuroendocrine Self'mentioning

confidence: 99%

Thymus Dysfunction in the Development of Type 1 Diabetes and Endocrine Autoimmune Diseases

Geenen

Dardenne

2009

European Endocrinology

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The discovery that thymic epithelium from many species expresses a large repertoire of genes encoding neuroendocrine and other tissuerestricted antigens has radically changed our knowledge of the pathogenic mechanisms underlying the development of organ-specific autoimmune diseases such as type 1 diabetes and autoimmune endocrine diseases. Rather than a breakdown of immunological selftolerance in periphery, there is mounting evidence that the diabetogenic autoimmune response may first arise from a thymus dysfunction in the central programming of β-cell self-tolerance. Insulin-like growth factor 2 (IGF-2) is the dominant member of the insulin gene/protein family expressed in thymic epithelial cells (TECs) from different species, and Igf2 -/-mice fail to programme complete tolerance to insulin.Based on the homology between insulin, the primary and immunogenic auto-antigen of type 1 diabetes, and IGF-2, the tolerogenic selfantigen of the insulin family, the design of a regulatory/negative self-vaccination for prevention against type 1 diabetes has been proposed and is under development.

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Section: Thymus Physiology and The Nature Of 'Neuroendocrine Self'mentioning

confidence: 99%

Thymus Dysfunction in the Development of Type 1 Diabetes and Endocrine Autoimmune Diseases

Geenen

Dardenne

2009

European Endocrinology

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“…La presence d'E. amylovora dans les fleurs saines a kt6 mentionnee par divers auteurs (Brulez & Zeller, 1981;Geenen et al, 1981), mais ceci n'est pas constant (Sutton & Jones, 1975;Dueck & Morand, 1975;Bonn, 198 1). En general l'association entre le niveau de population des fleurs et la prediction d'apparition n'est pas retrouvee.…”

Section: Cycle De La Bacterieunclassified

Réalisations récentes de la recherche sur le feu bactérien¹

Paulin¹

1987

EPPO Bulletin

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Un examen des travaux de recherches effectués sur Erwinia amylovora est présenté, qui concerne surtout les résultats des 10 dernières années. Les domaines de la pathogenèse et de la génétique microbienne, de l'épidémiologie et de l'étude de l'influence du climat sur la maladie, des moyens de lutte et de l'amélioration des plantes sont particulièrement examinés. Ce sont en effet les secteurs de recherche qui ont été les plus actifs, et dans lesquels des résultats substantiels ont éteé obtenus.

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Möglichkeiten der erfassung in der Luft befindlicher zellen des feuerbranderregers [Erwinia amylovora (Burrill) Winslow et al.]

Ficke

Ehrig

Nachtigall

et al. 1990

Zentralblatt für Mikrobiologie

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The System Used in Belgium to Monitor Erwinia Amylovora (Burrill) Winslow Et Al.

Cited by 4 publications

References 0 publications

Thymus Dysfunction in the Development of Type 1 Diabetes and Endocrine Autoimmune Diseases

Thymus Dysfunction in the Development of Type 1 Diabetes and Endocrine Autoimmune Diseases

Réalisations récentes de la recherche sur le feu bactérien¹

Möglichkeiten der erfassung in der Luft befindlicher zellen des feuerbranderregers [Erwinia amylovora (Burrill) Winslow et al.]

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The System Used in Belgium to Monitor Erwinia Amylovora (Burrill) Winslow Et Al.

Cited by 4 publications

References 0 publications

Thymus Dysfunction in the Development of Type 1 Diabetes and Endocrine Autoimmune Diseases

Thymus Dysfunction in the Development of Type 1 Diabetes and Endocrine Autoimmune Diseases

Réalisations récentes de la recherche sur le feu bactérien1

Möglichkeiten der erfassung in der Luft befindlicher zellen des feuerbranderregers [Erwinia amylovora (Burrill) Winslow et al.]

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Réalisations récentes de la recherche sur le feu bactérien¹