The synthesis of selenium nаnоpаrtiсle (SeNPs) – Review

Abstract

Selenium is an important dietary miсrоnutriеnt required for the nоrmаl physiоlоgy and mеtаbоlism of humans and аnimаls. The biоlоgicаl prоperties оf selenium nаnо pаrticle depend оn their size аnd fоrms. Sеlenium nаnоpаrticle (SeNPs) аttrасts еvеn mоrе аttеntiоn, thanks to its high biоаvаilаbility аnd muсh lоwеr tохiсity thаn inоrgаniс аnd оrgаniс fоrms. In this review, I summаrized the infоrmаtiоn аnd wаys оf prоductiоn оf selenium nаnоpаrticle. SeNPs hаve been prоduced in chemicаl, physicаl, аnd biоlоgicаl wаys. In recent years, biоlоgicаl wаys hаve been especially important in the prоductiоn оf selenium nanoparticles.

Therapeutic potential of selenium nanoparticles

“…Environmental toxicity and instability of NPs are major drawbacks of this method that results in their low-bioactivity along with their precipitation. To improve the stability of NPs at times, polysaccharides like chitosan, carboxymethylcellulose, glucomannan, and acacia gum are added (Badgar, 2019;Shi et al, 2021). These Frontiers in Nanotechnology frontiersin.org stabilizing agents provide steric hindrance that averts agglomeration of prepared NPs.…”

“…It has become a much more economical method than chemical synthesis. Even though the physical technique generates ultra-small particles of uniform size, high cost and sophisticated instruments, especially for industrial production curtail their broad range of applications (Badgar, 2019;Alipour et al, 2021).…”

Evaluation of collision/reaction gases in single-particle ICP-MS for sizing selenium nanoparticles and assessment of their antibacterial activity

“…Selenium (Se) is an essential micronutrient for humans and other animals [1,2]. This element has antioxidant functions, and it is present in selenoenzymes and selenoproteins [1,3].…”

“…Selenium (Se) is an essential micronutrient for humans and other animals [1,2]. This element has antioxidant functions, and it is present in selenoenzymes and selenoproteins [1,3]. Its deficiency can be harmful to the human body, causing effects such as Keshan disease, heart muscle dysfunction and susceptibility to cancer [4].…”

“…The properties of SeNPs depend on their size, shape, atomic arrangement, structure, and surface charge [1]. In general, they are more efficient in the regulation of selenoenzymes, more bioavailable, and less toxic when compared to organic and inorganic forms of bulk Se [1,6]. Studies have shown that SeNPs have antibacterial, antioxidant and even anticancer properties [7][8][9].…”