The synthesis of New 5-R-aminoazolo[1,5-a]pyrimidin-7-ones from an N,S-acetal Derivative of Meldrum’s Acid

Lyapustin, Daniil N.; Marusich, Irina V.; Fayzullina, Dilya F.; Ulomsky, E. N.; Матерн, А. И.; Русинов, В. Л.

doi:10.1007/s10593-023-03164-4

Chem Heterocycl Comp

2023

DOI: 10.1007/s10593-023-03164-4

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The synthesis of New 5-R-aminoazolo[1,5-a]pyrimidin-7-ones from an N,S-acetal Derivative of Meldrum’s Acid

Daniil N. Lyapustin

Irina V. Marusich

Dilya F. Fayzullina

et al.

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2024

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Cited by 2 publications

References 35 publications

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Recent Progress on the Synthesis, Biological Activity of Fused Pyrimidines from Azole Amines

Zhuang,

Wang,

Liu

et al. 2024

Eur J Org Chem

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Fused pyrimidines are a class of heterocyclic compounds that have gained considerable interest due to their extensive biological activities and potential applications in drug development. This review article aims to provide a comprehensive overview of the latest synthetic approaches to fused pyrimidines, including Michael reactions, multicomponent reactions, metal‐catalyzed reactions, photocatalytic reactions, peroxide‐mediated reactions, and inverse electron demand Diels–Alder reactions. Furthermore, the biological activities of these compounds, such as their ability to combat cancer and microbial infections, are also discussed. This review article summarizes the existing literature on the synthesis and biological activity of fused pyrimidines from 2020 to 2023. We hope this review article will inspire the development of more effective and less toxic fused pyrimidine drugs with well‐designed structures.

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Recent Progress on the Synthesis, Biological Activity of Fused Pyrimidines from Azole Amines

Zhuang,

Wang,

Liu

et al. 2024

Eur J Org Chem

View full text Add to dashboard Cite

show abstract

A synthesis of novel 5-methylsulfanylazolo[1,5-a]pyrimidin-7(4H)-ones and investigation of their chemical and cytotoxic properties

Lyapustin,

Fayzullina,

Marusich

et al. 2024

Chem Heterocycl Comp

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The synthesis of New 5-R-aminoazolo[1,5-a]pyrimidin-7-ones from an N,S-acetal Derivative of Meldrum’s Acid

Cited by 2 publications

References 35 publications

Recent Progress on the Synthesis, Biological Activity of Fused Pyrimidines from Azole Amines

Recent Progress on the Synthesis, Biological Activity of Fused Pyrimidines from Azole Amines

A synthesis of novel 5-methylsulfanylazolo[1,5-a]pyrimidin-7(4H)-ones and investigation of their chemical and cytotoxic properties

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