The synthesis and spectral characteristics of novel 6-(2-substituted-1,3,4-oxadiazol-5-yl)-2-phenylthieno[2,3-d]pyrimidine fluorescent compounds derived from 5-cyano-1,6-dihydro-4-methyl-2-phenyl-6-thioxopyrimidine

Synthesis and Bioassay of a New Class of Furanyl-1,3,4-Oxadiazole Derivatives

“…As a consequence of these characteristics, oxadiazoles have impacted drug discovery programs in numerous areas including muscarinic agonists [8,9], benzodiazepine receptor partial agonists [10,11], dopamine transporters [12], anti-rhinovirals [13], growth hormone secretogogues [14], 5-HT agonists[15], antispasmodics [16], nematocidal, fungicidal and microbicides [17], analgesics [18], anti-inflammatory agents [19,20], Fab I inhibitors as antibacterial agents [21], immnosuppressants [22], and also antiplatelet and antithrombotic agents [23], 5-HT antagonists [24], human NK 1 antagonists [25], They have been used as peptide mimetics due to their particular geometric and electrostatic properties [26,27]. Accordingly, in continuation of our work [28,29,30,31,32,33,34], a variety of heterocyclic derivatives involving some new oxadiazoles have been prepared from saccharide derivatives, and their chemistry and the effect of these derivatives on tyrosinase enzyme [35,36,37,38], which is the rate limiting step in melanine biosynthesis [39] as well as different biological actions were studied [40].…”

Thioxopyrimidine in Heterocyclic Synthesis III: Synthesis and Properties of Some Novel Heterocyclic Chalcone Derivatives Containing a Thieno[2,3‐d]pyrimidine‐Based Chromophore

“…According to Richter [48] and McLaren et al [49] the position of the color is distributed in the red-green area with hue angle ℎ ∘ 33.07-116.83 ∘ and radial chroma * of length 8. [35][36][37][38][39][40][41][42][43][44][45][46][47][48].08. Figure 1 shows a graph of CIE coordinates * versus * for selected dyes 6b, 6e, 6l, and 6n (an increasing * value represents an increase in redness, while a decrease in * represents a green hue shi).…”

“…Although a number of papers concerning the synthesis of chalcone compounds have been published, those containing a new heterocyclic system of thieno [2,3-d]-pyrimidinebased chromophores and application have not yet been reported. erefore, based on our previous works [37][38][39], we aim to report herein the preparation of a series of chalcone derivatives containing a thieno[2,3-d]-pyrimidinebased chromophore, and there was application to polyester �bers as disperse dyes. e spectral characteristics, dyeing properties, and colorimetric assessment of the dyes are also discussed.…”

Synthesis and fluorescent properties of some Furan‐tagged Thieno[2,3‐d]pyrimidines and Thieno[2,3‐d:4,5‐d']dipyrimidines

“…Many of these compounds were reported to act as antimicrobial, analgesic, anticancer, anti‐inflammatory, antihypertensive, anti‐oxidant, anti‐avian influenza, antiproliferative, anti‐HIV, and antidiabetic agents. Additionally; thienopyrimidine scaffolds with appropriate absorption and emission wavelengths act as fluorophores . These fluorescent organic compounds are widely used in bioprobes, organic light‐emitting diodes, photosensitizers, and optical chemosensors, which become important tools in analytical chemistry and medicine .…”