The synthesis and characterization of new polymerizable pyrimidines: Immobilization of the monomers onto hydrophilic graft copolymeric supports through radiation‐induced copolymerization–grafting

Abstract

Polymerizable quaternary allyl-pyrimidinium salts, that is, 1-allyl-4-amino-5-phenyl-pyrimidine (IV), 1-allyl-4-acetamido-5-phenyl-pyrimidine (V), 1-allyl-5-hydroxymethylamino-5-phenyl-pyrimidine (VI), and 1-allyl-pyrimidine (VIII) bromides, as well as 4-acrylamido-5-phenyl-pyrimidines IIЈ and IVЈ, were synthesized and characterized. Three of the activated pyrimidine derivatives, the two acrylamido and one allyl pyrimidine, were immobilized onto (Agar-g-co-HEMA)-X-TMPTA via graft copolymerization. Each copolymer system, based on 2-hydroxyethyl methacrylate (HEMA) grafted onto Agar followed by crosslinking with trimethyllopropane triacrylate (TMPTA), was prepared by radiation-induced copolymerization carried out in the simultaneous mode. The release properties of the immobilized pyrimidines were assessed in various aqueous media over a period of approximately 22 days.

Unique Intramolecular Electronic Communications in Mono-ferrocenylpyrimidine Derivatives: Correlation between Redox Properties and Structural Nature

“…The close absorption wavelength of the d-d transition in monoferrocenylpyrimidines compared to unsubstituted ferrocene (450 nm) indicates minute changes in the electronic delocalization in the cyclopentadienyl ring and insignificant influence of the electron withdrawing property of pyrimidine rings [28][29][30].…”