The symbiotic role of Wolbachia in Onchocercidae and its impact on filariasis

Bouchery, Tiffany; Lefoulon, Emilie; Karadjian, Grégory; Nieguitsila, Adélaïde; Martin, Coralie

doi:10.1111/1469-0691.12069

Cited by 68 publications

(63 citation statements)

References 123 publications

(165 reference statements)

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“…They can be found in many insect orders at various different frequencies, and were indeed associated with reproductive disorders [51], [53]. Additionally Wolbachia is an extensively studied symbiont that has been shown to induce many effects on its arthropod hosts, including effects on mosquito species hosts, an effect that has been recently employed in controlling the spread of the Dengue virus [55], [56]. The low concentration of Wolbachia and its dual localization pattern in B. tuberculata and T. acaciae suggests that it may play a role in reproductive manipulation; however, other effects cannot be ruled out and more research is required to confirm this assumption.…”

Section: Discussionmentioning

confidence: 99%

Diversity and Localization of Bacterial Endosymbionts from Whitefly Species Collected in Brazil

et al. 2014

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Whiteflies (Hemiptera: Aleyrodidae) are sap-sucking insect pests, and some cause serious damage in agricultural crops by direct feeding and by transmitting plant viruses. Whiteflies maintain close associations with bacterial endosymbionts that can significantly influence their biology. All whitefly species harbor a primary endosymbiont, and a diverse array of secondary endosymbionts. In this study, we surveyed 34 whitefly populations collected from the states of Sao Paulo, Bahia, Minas Gerais and Parana in Brazil, for species identification and for infection with secondary endosymbionts. Sequencing the mitochondrial Cytochrome Oxidase I gene revealed the existence of five whitefly species: The sweetpotato whitefly Bemisia tabaci B biotype (recently termed Middle East-Asia Minor 1 or MEAM1), the greenhouse whitefly Trialeurodes vaporariorum, B. tabaci A biotype (recently termed New World 2 or NW2) collected only from Euphorbia, the Acacia whitefly Tetraleurodes acaciae and Bemisia tuberculata both were detected only on cassava. Sequencing rRNA genes showed that Hamiltonella and Rickettsia were highly prevalent in all MEAM1 populations, while Cardinium was close to fixation in only three populations. Surprisingly, some MEAM1 individuals and one NW2 population were infected with Fritschea. Arsenopnohus was the only endosymbiont detected in T. vaporariorum. In T. acaciae and B. tuberculata populations collected from cassava, Wolbachia was fixed in B. tuberculata and was highly prevalent in T. acaciae. Interestingly, while B. tuberculata was additionally infected with Arsenophonus, T. acaciae was infected with Cardinium and Fritschea. Fluorescence in situ hybridization analysis on representative individuals showed that Hamiltonella, Arsenopnohus and Fritschea were localized inside the bacteriome, Cardinium and Wolbachia exhibited dual localization patterns inside and outside the bacteriome, and Rickettsia showed strict localization outside the bacteriome. This study is the first survey of whitely populations collected in Brazil, and provides further insights into the complexity of infection with secondary endosymionts in whiteflies.

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Section: Discussionmentioning

confidence: 99%

Diversity and Localization of Bacterial Endosymbionts from Whitefly Species Collected in Brazil

et al. 2014

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“…Several species of filarial nematodes that infect A. aegypti harbor obligate Wolbachia infections from supergroups C and D (Bouchery, Lefoulon, Karadjian, Nieguitsila, & Martin, ). Both Thongsripong et al () and Carvajal et al () detected Wolbachia in A. aegypti that aligned to supergroup C. Carvajal et al () observed substantial diversity in 16S rDNA and wsp sequences, with alignments to supergroups A, B, C, D, and J.…”

Section: Limitations Of Studies To Datementioning

confidence: 99%

An elusive endosymbiont: Does Wolbachia occur naturally in Aedes aegypti?

Ross

Callahan

Yang

et al. 2020

Ecology and Evolution

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Wolbachia are maternally inherited endosymbiotic bacteria found within many insect species. Aedes mosquitoes experimentally infected with Wolbachia are being released into the field for Aedes‐borne disease control. These Wolbachia infections induce cytoplasmic incompatibility which is used to suppress populations through incompatible matings or replace populations through the reproductive advantage provided by this mechanism. However, the presence of naturally occurring Wolbachia in target populations could interfere with both population replacement and suppression programs depending on the compatibility patterns between strains. Aedes aegypti were thought to not harbor Wolbachia naturally but several recent studies have detected Wolbachia in natural populations of this mosquito. We therefore review the evidence for natural Wolbachia infections in A. aegypti to date and discuss limitations of these studies. We draw on research from other mosquito species to outline the potential implications of natural Wolbachia infections in A. aegypti for disease control. To validate previous reports, we obtained a laboratory population of A. aegypti from New Mexico, USA, that harbors a natural Wolbachia infection, and we conducted field surveys in Kuala Lumpur, Malaysia, where a natural Wolbachia infection has also been reported. However, we were unable to detect Wolbachia in both the laboratory and field populations. Because the presence of naturally occurring Wolbachia in A. aegypti could have profound implications for Wolbachia‐based disease control programs, it is important to continue to accurately assess the Wolbachia status of target Aedes populations.

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“…One major dissimilarity between O. volvulus and L. loa is that O. volvulus is Wolbachia -dependent, whereas L. loa is naturally Wolbachia -free (Fig.4b) 26, 27, 28, 29, 30. In the case of M. perstans , this nematode is host to the supergroup F Wolbachia strain, which is phylogenetically distinct from the supergroup C/D endosymbionts normally present in filarial nematodes including O. volvulus (supergroup C) and L. sigmodontis (supergroup D) 31, 32, 33. One additional Wolbachia -related aspect having the potential to separate O. volvulus infections from other infections is that a predicted N -acetyltransferase protein has been identified in the Wolbachia endosymbiont of O. volvulus str.…”

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confidence: 99%