The Susceptibility of Bacteroides fragilis to 24 Antibiotics

Kislak, Jay Ward

doi:10.1093/infdis/125.3.295

Cited by 140 publications

(33 citation statements)

References 13 publications

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“…Our results confirm that clindamycin is the drug of choice as suggested by the in-vitro studies of Ingham et al (1968), Kislak (1972), and the report of Tracy et al (1972). Other antibiotics may be useful, however, especially erythromycin and lincomycin, which may be given parenterally as well as by mouth.…”

Section: Discussionsupporting

confidence: 92%

Regression of the Forbes-Albright syndrome after pituitary apoplexy.

McLaren¹,

Keet²

1973

BMJ

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Section: Discussionsupporting

confidence: 92%

Regression of the Forbes-Albright syndrome after pituitary apoplexy.

McLaren¹,

Keet²

1973

BMJ

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“…The strains of Bacteroides reported here were resistant to penicillin and ampicillin, therefore other antibiotics should be used to treat the infections. Our results confirm that clindamycin is the drug of choice as suggested by the in-vitro studies of Ingham et al (1968), Kislak (1972), and the report of Tracy et al (1972). Other antibiotics may be useful, however, especially erythromycin and lincomycin, which may be given parenterally as well as by mouth.…”

Section: Discussionsupporting

confidence: 87%

Bacteroides Infection among Hospital Patients

Okubadejo¹,

Green²,

Payne³

1973

BMJ

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SummaryIn an 18-month period a total of 118 isolates of Bacteroides species, mainly Bacteroidesfragilis, were grown from 112 hospital patients with various conditions. The infections were severe and were associated with serious operations such as intestinal surgery for carcinoma and postpartum hysterectomy. Blood cultures were often found to be positive too late in the course of infection for prompt and successful antibiotic therapy to be given. All the Bacteroides species tested were sensitive to clindamycin and co-trimoxazole. We suggest that clindamycin should be added to an empirical antibiotic regimen for the treatment of patients prone to the infection.

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“…Ingham, Selkon, Codd, and Hale (1970) showed that 0 3 ,ug-1 25 ,g clindamycin was bactericidal to strains of B. fragilis. The high sensitivity of bacteroides to clindamycin and to a slightly lesser extent, the parent compound, lincomycin, has been confirmed by Kislak (1972), Bodner et al (1972), andMartin, Gardner, andWashington (1972). In this series only one of 1067 strains tested was found to be resistant to clindamycin.…”

Section: Discussionsupporting

confidence: 52%

Incidence and isolation of Bacteroides species from clinical material and their sensitivity to antibiotics

Mitchell

1973

J Clin Pathol

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One thousand and sixty-seven strains of anaerobic Gram-negative bacilli were isolated from routine clinical material between January 1971 and December 1972. Most of the strains were isolated from sites allied to the lower intestine and genito-urinary tract. Resistance to tetracycline was present in 39·2% of strains tested. In contrast only one strain was found resistant to clindamycin. It is suggested that the recovery of anaerobes from material sent to the laboratory depends largely on the efficiency of the anaerobic system used.

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The Susceptibility of Bacteroides fragilis to 24 Antibiotics

Cited by 140 publications

References 13 publications

Regression of the Forbes-Albright syndrome after pituitary apoplexy.

Regression of the Forbes-Albright syndrome after pituitary apoplexy.

Bacteroides Infection among Hospital Patients

Incidence and isolation of Bacteroides species from clinical material and their sensitivity to antibiotics

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