Patients and Methods PatientsAll patients who underwent surgical repair of isolated pulmonary valve stenosis at the Mayo Clinic between 1956 and 1967 are included in this study. These dates were selected to allow a minimum follow-up of 20 years (or until death); the maximum follow-up is 30 years. The diagnosis of isolated pulmonary stenosis included patients in whom the only other congenital cardiac abnormality was an atrial septal defect but with less than 20% left-to-right shunt (quantitated by oxygen saturations by the Van Slyke method). Patients with pulmonary valve atresia or the hypoplastic right heart syndrome were excluded from this study. These criteria were met by 191 patients, of whom 99 (52%) were male. The mean (±+ SD) age at operation was 13.6±+13.1 years (range, 3 days to 68 years; median, 9 years) ( Figure IA). Associated conditions included atrial septal defect in 42 patients, patent foramen ovale in 30 patients, and anomalous origin of the left anterior descending coronary artery from the right coronary artery in one patient. No other congenital cardiac abnormalities were present.The follow-up status of the patients was determined by examination at this institution or by a detailed questionnaire. If interim death, hospitalization, or a cardiovascular event had occurred, either