2022
DOI: 10.3390/life12070982
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The Surgical Treatment of Osteoarthritis

Abstract: Osteoarthritis is a degenerative condition affecting the whole joint with the underlying bone, representing a major source of pain, disability, and socioeconomic cost worldwide. Age is considered the strongest risk factor, albeit abnormal biomechanics, morphology, congenital abnormality, deformity, malalignment, limb-length discrepancy, lifestyle, and injury may further increase the risk of the development and progression of osteoarthritis as well. Pain and loss of function are the main clinical features that … Show more

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Cited by 11 publications
(7 citation statements)
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“…This approach is crucial for ensuring the best possible outcome in these complex Lisfranc injury cases [ 25 ]. Specific surgical interventions and techniques can be guided to some extent by secondary objectives, such as the preservation of articular cartilage to prevent post-operative osteoarthritis [ 26 ].…”
Section: Reviewmentioning
confidence: 99%
“…This approach is crucial for ensuring the best possible outcome in these complex Lisfranc injury cases [ 25 ]. Specific surgical interventions and techniques can be guided to some extent by secondary objectives, such as the preservation of articular cartilage to prevent post-operative osteoarthritis [ 26 ].…”
Section: Reviewmentioning
confidence: 99%
“…For most patients, conservative management is often piecemeal, and various interventions are tried as individual “one-offs” until something is found to offer relief. When such an intervention subsequently fails, the search continues until more invasive options are entertained; such options include pre-joint replacement surgical interventions such as osteotomies [ 81 ], drilling/microfracture of the bone [ 94 , 95 ], or debridement alone or in combination with other treatments [ 96 , 97 , 98 ]. While many of these invasive surgeries offer transient relief for a number of patients, they have not been evaluated for effectiveness regarding knee OA subsets as defined in this review.…”
Section: Implications From Subtyping For Conservative Treatment For K...mentioning
confidence: 99%
“…Current therapeutic modalities encompass patient education, exercise regimens, weight management, physiotherapy, and pharmacotherapy [ 4 ]. Surgical interventions, such as total knee arthroplasty (TKA), are primarily reserved for advanced degenerative knee joint disease [ 5 ].…”
Section: Introductionmentioning
confidence: 99%