1922
DOI: 10.1097/00000658-192210000-00016
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The Surgical Relief of Intestinal Foci of Infection in Cases of Arthritis Deformans

Abstract: IN I9I5 the writer reported before the Surgical Section of the American Medical Association, a series of fourteen cases of chronic arthritis operated upon for the removal of an intestinal focal infection. Of this list two have died, four are untraced, three are not improved, one has had a complete arrest of the disease, but is unable to-walk on account of joint fixation. Four are restored to normal activity. We attribute our failure to show a higher percentage of cures to our surgery. These early patients were… Show more

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Cited by 25 publications
(5 citation statements)
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“…He then stated, quite prophetically, that ‘no study of a case of arthritis is complete without a careful investigation of the gastro-intestinal tract’. 2 …”
Section: Introductionmentioning
confidence: 99%
“…He then stated, quite prophetically, that ‘no study of a case of arthritis is complete without a careful investigation of the gastro-intestinal tract’. 2 …”
Section: Introductionmentioning
confidence: 99%
“…Gut involvement in the pathogenesis of rheumatic diseases was proposed by Smith (55), and more recent studies have investigated this further, suggesting that as the intestinal bacterial flora may be affected by diet, a diet that could influence the intestinal flora might have an effect on disease activity (54,56). Klebsiella pneumoniae was suggested as a trigger for AS and Crohn's disease based on molecular mimicry, and a low starch diet was proposed as a means of reducing Klebsiella bacteria in the gut and, hence, further pathological damage (10-13).…”
Section: Discussionmentioning
confidence: 99%
“…Snyder and Fineman's perspective is that in a subset of cases of arthritis, the lack of response to conventional treatment may be due to toxin absorption from the gastrointestinal track. Snyder and Fineman cite several clinicians in addition to Pemberton who have this perspective (Persson, 1923;Smith, 1922;Carter 1923;Forbes 1924). Thus as late as 1927, the autointoxication hypothesis has not gone away.…”
Section: Clinical Experience With Colonic Irrigationsmentioning
confidence: 99%