The successful use of radiotherapy for osteoblastoma

Singer, Jonas; Deutsch, G.P.

doi:10.1016/s0936-6555(05)80867-2

Cited by 15 publications

(3 citation statements)

References 7 publications

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“…Of 18 reported cases of temporal bone osteoblastomas, five presented with symptoms of cranial nerve VII and/or VIII involvement or conductive hearing loss. The symptoms include tinnitus, hearing loss or disturbance, hypogeusia, facial hemiparesis, and intermittent bleeding [25,31,34,39,42,46,[49][50][51]58]. On examination, a mass may be visualized protruding into the external auditory canal [25,31,34,46,49,51].…”

Section: Presentationmentioning

confidence: 99%

Clinical characteristics and diagnostic imaging of cranial osteoblastoma

Pelargos

Nagasawa

Ung

et al. 2015

Journal of Clinical Neuroscience

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Section: Presentationmentioning

confidence: 99%

Clinical characteristics and diagnostic imaging of cranial osteoblastoma

Pelargos

Nagasawa

Ung

et al. 2015

Journal of Clinical Neuroscience

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“…different modes of management involving osteoid osteoma and osteoblastoma have been assessed. they include radiotherapy, chemotherapy (15,16) and percutaneous radiofrequency ablation (3). the methods mentioned above may be useful particularly in patients with recurrent aggressive tumors or in patients with surgically unresectable tumors.…”

Section: Discussionmentioning

confidence: 99%

Aggressive osteoblastoma of the sphenoid bone

Kukwa¹,

Oziȩbło²,

Oecińska³

et al. 2010

Oncology Letters

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Abstract. For osteoblastoma, with its predilection for the spinal column and appendicular skeleton, the skull is an unusual site, and paranasal sinus involvement is very rare. Herein, we report on a case in which the disease was located within the sphenoid bone. to the best of our knowledge, this is the 4th reported case of osteoblastoma with a sphenoid origin (1). We report an osteoblastoma of the sphenoid sinus in a 12-year-old girl who presented with exophthalmos. computed tomography (ct) demonstrated an expansile lesion of the sphenoid which caused the orbital contents to be compressed and deviated to the right. In the magnetic resonance imaging scan, the lesion was found to invade the cranial base in the frontal and temporal region, approximating to the cavernous sinus and internal carotid artery on the right. Bilateral fronto-orbital craniotomy was performed. Histologically, the lesion was composed of proliferating osteoblasts along with vascular stroma. the tumor was described as an aggressive osteoblastoma. In the follow-up ct four months later, a pathological mass was observed in the area of the nasal septum, and a signal void was present on all sequences in the densely sclerotic areas. A second resection was performed. the patient has been disease-free for 61 months. Herein, we present the diagnosis and management of this unusual lesion. the histopathology and the imaging characteristics are shown.

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“…Nevertheless, there are reports of successful use of primary radiotherapy treatment of osteoblastomas in non-resectable sites (e.g. petrous bone or recurrent osteoblastoma) in both adults and children, with no recurrence or transformation after long-term follow up 15 – 18 …”

Section: Discussionmentioning

confidence: 99%