2014
DOI: 10.1517/17460441.2014.905539
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The successes and challenges of open-source biopharmaceutical innovation

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Cited by 7 publications
(4 citation statements)
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“…The current business model of the pharmaceutical industry is unable to meet all medical needs, especially in the areas of neglected and rare diseases. In response, a variety of open source models have been implemented by a variety of organizations [56][57][58] (http://opensourcemalaria.org/; http:// www.osdd.net/) and there has been some recent discussion regarding the viability of such an open source business model expansion beyond the area of neglected diseases [59,60] (http:// www.opensourcepharma.net/). An interesting approach for drug development is the crowdsourcing of clinical trial design [61,62].…”
Section: Concluding Remarks and Discussionmentioning
confidence: 99%
“…The current business model of the pharmaceutical industry is unable to meet all medical needs, especially in the areas of neglected and rare diseases. In response, a variety of open source models have been implemented by a variety of organizations [56][57][58] (http://opensourcemalaria.org/; http:// www.osdd.net/) and there has been some recent discussion regarding the viability of such an open source business model expansion beyond the area of neglected diseases [59,60] (http:// www.opensourcepharma.net/). An interesting approach for drug development is the crowdsourcing of clinical trial design [61,62].…”
Section: Concluding Remarks and Discussionmentioning
confidence: 99%
“…This is also linked to the discussion of open innovation in the biopharmaceutical industry [48]. In this industry, open innovation spans a wide range of activities from drug discovery through data sharing to product development and clinical test platforms [49]. Mazzola et al [50] empirically tested that open innovation is actually beneficial to firms' performance in biopharmaceutical industry.…”
Section: Business Models Of Biopharmaceutical Industrymentioning
confidence: 99%
“…During the past few years, there has been an important increase in open data initiatives to promote the availability of free research-based tools and information. 1 While there is still some resistance to open data in some chemistry and drug discovery elds, the availability of information has been a necessity for other research elds such as genomics, proteomics and bioinformatics. The Human Genome Project was paramount to the open-source movement in proteomics and genomics, demonstrating that a global community can be more successful and efficient in analyzing data than a single individual can.…”
Section: Introductionmentioning
confidence: 99%