The Success of Cataract Surgery and the Preoperative Measurement of Retinal Function by Electrophysiological Techniques

Abstract

Purpose. To study the effect of different electrophysiological methods to evaluate retinal function prior to cataract surgery. Methods. Cataract patients who had no significant other eye disease were chosen. VA, pattern visual evoked potential (PVEP), electroretinogram (ERG), and multifocal electroretinogram (mfERG) responses were measured from 150 cataract patients and 20 control subjects. Results. When the preoperative VA was more than 0.3 in cataract patients, the amplitude of PVEP was not significantly different between cataract and control subjects. The amplitude of central point mfERG was significantly lower in cataract patients compared with control group from HM to 0.8 of preoperative VA. The 95% confidence intervals (CIs) of the amplitudes of center point mfERG were calculated for a range of preoperative VA values. Most of the patients within 95% CI of the center point mfERG had a postoperative VA more than 0.5. Conclusions. The amplitude of central point mfERG in cataract patients was the most relevant parameter to the preoperative VA compared with PVEP and ERG. The 95% CI of the amplitude of central point mfERG for each level of VA could help to evaluate preoperative macular function which is used to predict the outcome of cataract surgery.

Combined Intravitreal Dexamethasone Implant and Cataract Surgery in Patients with Diabetic Retinopathy: Effect on Retinal Morphology and Function

“…In healthy subjects, the amplitude of the b wave was closely correlated with postoperative BCVA for the scotopic 3.0 ERG response [30].…”

Quality Control Procedures and Baseline Values for Electroretinography, Perimetry, Color Vision, and Visual Acuity in an International Multicenter Study: Observations from a Safety Trial in Chronic Stable Angina Pectoris

“…45,46 The cohort included some individuals with moderate age-related cataract and/or other ophthalmologic conditions common in advanced age to the extent that they were not considered an exclusion criterion. The presence of moderate age-related cataract does not affect either the peak time or the amplitude of the Ganzfeld ERG 47 ; however, such manifestation does Table 6. The Coefficients of Variation (SD/Mean), Expressed as a Percentage, for the Data in Table 5 Current adversely influence the visual field measurement.…”

Single flash electroretinograms of mature cataractous and fellow eyes

“…In recent studies, Miura et al mentioned that the presence of cataracts should be taken into consideration when interpreting flicker ERGs, 6 and An et al showed that the amplitude of central point multifocal ERG was significantly lower in cataract patients. 5 However, Cruz and Adachi-Usami observed that, in a single flash ERG, the mean amplitudes of the a- and b-waves were slightly reduced in the mature cataractous eyes as compared to those of the fellow eyes, but the difference was not significant. 3 In our study, the light-absorbing effect of the cataract, based on the amplitudes of a- and b-waves, was approximately 8% and 6%, respectively, instead of the 0.5 log unit observed by them.…”

“…In a previous study with 22 patients with mature cataract, it was observed that single flash ERG values decreased depending on the degree of cataract opacity, even though the difference was not significant 3 and Uji showed that the amplitude of ERG b-wave was significantly increased after cataract surgery in comparison to the preoperative result. 4 An et al showed that the amplitude of central point multifocal ERG was significantly lower in cataract patients compared with control group, from “hand movement” (HM) to 0.8 of preoperative VA. 5 Furthermore, Miura et al reported that the presence of cataracts of Grade 2 or higher affect the amplitude and the implicit time of flicker ERGs. 6 However, ERG information in patients with mature cataract is still limited.…”