The subjective quality of life in deficit and nondeficit schizophrenic patients

Delamillieure, Pascal; Ochoa-Torres, Dominique; Vasse, T.; Brazo, P.; Gourévitch, Raphaël; Langlois, Sophie; Assouly-Besse, F; Elst, A. Van Der; Morello, Rémy; Guelfi, Julien Daniel; Petit, Michel; Dollfus, Sonia

doi:10.1016/j.eurpsy.2005.04.010

Cited by 9 publications

(4 citation statements)

References 10 publications

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“…Apathy, for example, can compromise compliance with antipsychotic pharmacotherapy, which tends to be poor among schizophrenic patients in general; and inadequate adherence to therapy is a main contributor to the risk of relapse. In addition, a significant correlation between negative symptoms and decreased quality of life has been demonstrated in several [11,16,17,32] although not all [15] reports.…”

Section: The Relevance Of the Diagnosismentioning

confidence: 99%

Clinical evaluation of negative symptoms in schizophrenia

Möller¹

2007

Eur. psychiatr.

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The florid positive symptoms of schizophrenia (hallucinations, delusions, grossly disordered thinking) are often obvious. By comparison, negative symptoms (flattened affect, impoverished speech, apathy, avolition, anhedonia) are subtler and more difficult to recognize and diagnose. However, there is increasing recognition of the importance of negative symptoms in patients with schizophrenia. Secondary negative symptoms attributable to such factors as unrelieved positive symptoms, the adverse effects of antipsychotic pharmacotherapy, or social isolation may subside with resolution of such factors. In contrast, primary negative symptoms are an intrinsic aspect of schizophrenia; they are persistent and have been associated with poorer clinical outcomes. Although the lack of a reliably effective treatment for negative symptoms is a serious unmet need in this patient population, accurate diagnosis is still important. Assessment of suspected negative symptoms, using validated rating scales, can help to rule out comorbid affective or cognitive disorders that may mimic negative symptoms and to distinguish primary negative symptoms from potentially reversible secondary negative symptoms. This article reviews the definitions and classification of negative symptoms, compares the tools available for their assessment, and offers practical clinical algorithms for sorting through the differential diagnosis.

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Section: The Relevance Of the Diagnosismentioning

confidence: 99%

Clinical evaluation of negative symptoms in schizophrenia

Möller¹

2007

Eur. psychiatr.

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“…4,5 Moreover, these symptoms are responsible for impaired social functioning 6,7 and have a deleterious impact on the quality of life. 8,9 In this context, the use of standardized assessment tools may be pertinent 10 to improve the identification of negative symptoms and their treatment. A recent review of the literature included nearly 20 tools used to assess the negative dimension of schizophrenia.…”

Section: Introductionmentioning

confidence: 99%

Self-Evaluation of Negative Symptoms: A Novel Tool to Assess Negative Symptoms

Dollfus

Mach

Morello

2015

SCHBUL

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Many patients with schizophrenia have negative symptoms, but their evaluation is a challenge. Thus, standardized assessments are needed to facilitate identification of these symptoms. Many tools have been developed, but most are based on observer ratings. Self-evaluation can provide an additional outcome measure and allow patients to be more engaged in their treatment. The aim of this study was to present a novel tool, Self-evaluation of Negative Symptoms (SNS), and demonstrate its validity. Forty-nine patients with schizophrenia and schizoaffective disorders according to DSM-5 were evaluated. Cronbach's coefficient (α = 0.867) showed good internal consistency. Factor analysis extracted 2 factors (apathy and emotional) that accounted for 75.2% of the variance. The SNS significantly correlated with the Scale of Assessment of Negative Symptoms (r= 0.628) and the Clinician Global Impression on the severity of negative symptoms (r= 0.599), supporting good convergent validity. SNS scores did not correlate with level of insight (r= 0.008), Parkinsonism (r= 0.175) or Brief Psychiatric Rating Scale positive subscores (r= 0.253), which indicates good discriminant validity. The intrasubject reliability of the SNS revealed excellent intraclass correlation coefficients (ICC = 0.942). Taken together, the results show that the SNS has good psychometric properties and satisfactory acceptance by patients. The study also demonstrates the ability of patients with schizophrenia to accurately report their own experiences. Self-assessments of negative symptoms should be more widely employed in clinical practice because they may allow patients with schizophrenia to develop appropriate coping strategies.

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“…Todos estos aspectos pueden verse comprometidos en distintos grados según la complejidad del cuadro clínico en personas que presenten esquizofrenia crónica en distintas fases de su enferme-dad como lo demuestran Giner et al (2001) y Karow, Moritz, Lambert y Schoder y Krausz (2005) que constatan que los síntomas afectivos menos sicóticos, como los depresivos y los ansiosos influyen directamente sobre la calidad de vida de los enfermos. Lo mismo ocurre con la sintomatología residual presente en pacientes sicóticos que han recibido tratamiento con neurolépticos clásicos (Delamillieure et al, 2005). Es por esto que nos parece que esta escala no es representativa para evaluar esta función en este grupo particular de personas.…”

Section: Analisis De Los Resultadosunclassified

Validación De Una Escala De Calidad De Vida en Un Grupo De Personas Con Esquizofrenia De La Region Metropolitana - Chile

et al. 2007

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RESUMENEl estudio evalúa las propiedades psicométricas de la versión española de la Short form-36 Health Survey (SF-36), diseñada por el Medical Outcomes Study y la validada por Alonso (1999) en personas con esquizofrenia crónica. Para esto, se realizó una aplicación piloto que mostró la necesidad de realizar adaptaciones en el instrumento. Luego, el instrumento adaptado fue aplicado en la Región Metropolitana a 99 sujetos con esquizofrenia. Se utilizó el programa SPSS para el análisis estadístico, el cual mostró que el comportamiento de los ítemes permite aplicarla en una versión modificada.Palabras claves: Calidad de vida, esquizofrenia, escala de evaluación. ABSTRACTThe study evaluates the psychometric properties of the spanish version of the Short form-36 Health Survey (SF-36), in people with schizophrenia. The SF-36 inventory designed by the Medical Outcomes Study and the one validated by Alonso (1999) were used. With this purpose, a pilot application was carried out, showing that it was necessary to make some adaptations to the instrument. Then, the adapted instrument was applied in ninety nine person with schizophrenia from the Metropolitan Region. The program SPSS used for the statistical analysis showed that the behaviour of items allowed to apply it in a modified version.

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The subjective quality of life in deficit and nondeficit schizophrenic patients

Cited by 9 publications

References 10 publications

Clinical evaluation of negative symptoms in schizophrenia

Clinical evaluation of negative symptoms in schizophrenia

Self-Evaluation of Negative Symptoms: A Novel Tool to Assess Negative Symptoms

Validación De Una Escala De Calidad De Vida en Un Grupo De Personas Con Esquizofrenia De La Region Metropolitana - Chile

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