“…previous device infection, hemodialysis, chronic immunosuppression therapy, immunodeficiencies, artificial heart valves etc) [9, 13]. Pocket infections can occur with the S-ICD (between 5 and 10%, not so different compared to transvenous devices), but a striking observation is that the resolution of the infection with antibiotic therapy is possible in the majority of cases, without explantation of the system [9, 10, 19]. Even when explantation becomes necessary, it represents a much more simple and safer procedure compared to endovascular lead extraction; this is particularly important in young patients with a long life expectancy and high lead failure rate due to active lifestyles [9, 10, 11].…”