The Study on the Difference of EEG Results between Anger Syndrom and Major Depressive Disorder

Kim, Ka-Na; Choi, Myoungsub; Ji, Sang-Eun; Cho, Seung-Hun

doi:10.7231/jon.2013.24.spc1.055

Cited by 1 publication

(2 citation statements)

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“…Previous EEG studies have demonstrated that the brain waves of subjects with MDD differ significantly from those without MDD. There are distinguishable patterns in resting EEG waves between MDD and non-MDD subjects, and activation of the prefrontal alpha waves is more prominent in the left hemisphere than in the right in patients with MDD [38, 39]. The EEG records obtained in this study will be analyzed with a focus on the balance of prefrontal alpha waves between the right and left hemispheres.…”

Section: Discussionmentioning

confidence: 99%

“…Electrodes will be attached at two sites (F3, F4) out of the 10–20-site system of the scalp to evaluate the balance of prefrontal alpha waves from the right and left hemispheres. Previous EEG studies have confirmed that a characteristic, asymmetric pattern of resting frontal activity can be observed in people with MDD that is unlike measurements made in the non-MDD population [38, 39]. …”

Section: Methodsmentioning

confidence: 99%

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Electroacupuncture plus moxibustion therapy for patients with major depressive disorder: study protocol for a randomized controlled trial

Kim

Choi

Kim

et al. 2017

Trials

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BackgroundMajor depressive disorder (MDD) is one of the most prevalent mental health disorders and has a significant societal economic burden. Antidepressants and cognitive behavioral therapy are two primary interventions for the standardized treatment of MDD. However, their weaknesses, such as a low response rate, a high risk of adverse events from medication, and the high cost of cognitive behavioral therapy, have resulted in a need for complementary and alternative medicine (CAM). Among the various therapeutic interventions in CAM, electroacupuncture and moxibustion have been widely used to treat various mental illnesses, including MDD. The aim of this study is to evaluate the feasibility of conducting a full-scale randomized controlled trial to investigate the efficacy and safety of electroacupuncture plus moxibustion therapy for MDD.Methods/designWe will include patients between the ages of 19 to 65 years with MDD. A total of 30 participants will be recruited, and they will be randomly allocated into two groups at a 1:1 ratio. Patients in the treatment and control groups will, respectively, receive real and sham electroacupuncture/moxibustion treatments, for a total of 20 sessions over 8 weeks. The primary outcome will be the Hamilton Rating Scale for Depression, and the secondary outcomes will be Beck’s Depression Inventory, the Insomnia Severity Index, the State-Trait Anxiety Inventory, the EuroQol 5-Dimension Index, the Measure Yourself Medical Outcome Profile version 2, and electroencephalography. Adverse events will be monitored at each visit to assess safety. All outcomes will be assessed and analyzed by researchers blinded to the treatment allocation.DiscussionThis is a two-armed, parallel-design, patient-assessor blinded, multicenter, randomized, sham-controlled pilot clinical trial. Data will be analyzed before and after treatment and during a 4-week follow-up. The results of the trial will provide a basis for further studies assessing the efficacy and safety of electroacupuncture plus moxibustion treatment for MDD.Trial registrationKorean Clinical Trial Registry, CRIS-KCT0001810. Registered on 5 February 2016 (retrospectively registered; date of enrollment of the first participant to the trial: 2 December 2015).Electronic supplementary materialThe online version of this article (doi:10.1186/s13063-016-1741-2) contains supplementary material, which is available to authorized users.

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Section: Discussionmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%

Electroacupuncture plus moxibustion therapy for patients with major depressive disorder: study protocol for a randomized controlled trial

Kim

Choi

Kim

et al. 2017

Trials

View full text Add to dashboard Cite

show abstract

The Study on the Difference of EEG Results between Anger Syndrom and Major Depressive Disorder

Abstract: We will discuss the differences on EEG results of Post-traumatic embitterment disorder (PTED) and Major depressive disorder (MDD). Methods : We measured EEG on 21 sites (Fp1,

Cited by 1 publication

References 8 publications

Electroacupuncture plus moxibustion therapy for patients with major depressive disorder: study protocol for a randomized controlled trial

Electroacupuncture plus moxibustion therapy for patients with major depressive disorder: study protocol for a randomized controlled trial

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