The continuous improvement of virtual reality and interactive technology has led to a broader and deeper application in related fields, especially image design. In image design, creating usage scenarios for portable interactive experience products based on virtual reality and interactive technology can optimize and improve key parameters for real 3D techniques, thereby building a more comprehensive image design. This article constructs a three-dimensional image model of marine organisms and scenarios based on multi-sensory interactive interface generation technology and information fusion optimization ANNs-DS algorithm, targeting the image scenarios of product design. The relevant model information and parameter changes are analyzed. The results indicate that in the process of multi-sensory interface interactive image design, the virtual reality image design implemented using ANNs-DS information fusion algorithm can enhance participants' multi-sensory visual experience of the interactive interface. The reasonable degree between objects in the interactive interface and the scene space image is basically within the range of 0.85-0.95. The fluency in different scenarios can be significantly improved. Therefore, virtual reality and interactive technology have laid the foundation for developing interactive image design.