The Study of Pulmonary Functions in Patient of Type 2 Diabetes Mellitus

Abstract

BACKGROUND Diabetes mellitus and the complications associated with it has become a reason of concern due to health problems related to them. AIM To study and compare the pulmonary function parameters like FVC, FEV1, FEV1%, PEFR, FEV 25-75% in patients with type 2 diabetes mellitus and control group. SETTINGS AND DESIGN This study was planned to assess pulmonary functions in type 2 diabetic patients. METHODS AND MATERIALS We evaluated 60 diabetic male subjects in the age group 41-60 years. For controls, 60 age matched healthy male subjects were taken. PFT was carried out with Computerised Medspiror. STATISTICAL ANALYSIS The various data was collected, compiled, statistically analysed by unpaired t-test and conclusion drawn. RESULTS The present study results showed a significant decrease in the mean values of FVC, FEV1, PEFR and FEF 25-75% in diabetic subjects as compared to controls. FEV1% was significantly increased in diabetic persons. CONCLUSION Chronic hyperglycaemia leads to non-enzymatic glycosylation of extracellular matrix leading decrease in lung compliance, which is responsible for restrictive type of pulmonary impairment of lung functions.