The Study of Predictive Value of Uterine Artery Doppler in Incidence of Preeclampsia and Intrauterine Growth Restrictions in Pregnant Women

Abstract

Objectives: Preeclampsia is considered as one of the most important causes of death among pregnant women all around the world. This study aimed to study the predictive value of uterine artery Doppler ultrasonography in the incidence of preeclampsia and the intrauterine growth restriction (IUGR) in pregnant women who attended Fatemieh hospital. Materials and Methods: This study was performed by the prospective cohort method and the statistical population included 108 pregnant women, in their 18-22 weeks of pregnancy, with a singleton pregnancy who referred to the prenatal Fatemieh Hospital of Hamadan during 2013-2016. The uterine artery Doppler ultrasonography was performed and the incidence of IUGR and the occurrence of preeclampsia in the followed pregnancy was evaluated in these patients. Data were analyzed by SPSS 16.0 using the chi-square and Mann-Whitney U statistical tests. Results: The mean difference of pulsatility index (PI) in patients with preeclampsia was statistically significant compared to healthy individuals (P=0.001). In addition, the mean difference of PI in individuals with infants suffering from IUGR was statistically significant compared with the infants not suffering from the IUGR (P=0.001). Further, the incidence of preeclampsia and IUGR in women with a bilateral notch in ultrasonography was significantly greater than those of the women with no report of a bilateral notch in ultrasonography (P=0.001). Conclusions: Therefore, Doppler ultrasonography of the uterine artery has a predictive value in preeclampsia among pregnant women.

Association between transabdominal uterine artery Doppler and small-for-gestational-age: a systematic review and meta-analysis

“…In this meta-analysis, we found a significant association between the notch presence and SGA and that notch presence was significantly associated with the increased odds of SGA. The similar finding was reported in former studies [ 5 , 13 , 35 ]. Borna et al found that the incidence of SGA in women with notch was significantly greater than women without notch in ultrasonography [ 13 ].…”

“…In this meta-analysis, we observed higher levels of UtA-PI and UtA-RI in women with SGA compared to those without SGA during the whole pregnancy. Previous studies have reported the similar findings [ 13 , 31 ]. Borna et al performed a study to identify patients at the risk of SGA using UtA, and they observed that mean UtA-PI in women with SGA newborns was significantly higher than those without SGA newborns [ 13 ].…”

“…Previous studies have reported the similar findings [ 13 , 31 ]. Borna et al performed a study to identify patients at the risk of SGA using UtA, and they observed that mean UtA-PI in women with SGA newborns was significantly higher than those without SGA newborns [ 13 ]. Similarly, Maged et al showed that UtA-RI was significantly higher in women who developed SGA compared to controls [ 31 ].…”

“…Mean PI and RI were the average from the left and right uterine arteries [ 12 ]. Notch presence meant the unilateral or bilateral notch in the diastolic notch [ 13 ]. Abnormal UtA includes: the presence of diastolic notch, high RI (RI > 95%, RI > 75%, RI > 90%), or high PI (PI > 95%) [ 13 – 16 ].…”

“…Notch presence meant the unilateral or bilateral notch in the diastolic notch [ 13 ]. Abnormal UtA includes: the presence of diastolic notch, high RI (RI > 95%, RI > 75%, RI > 90%), or high PI (PI > 95%) [ 13 – 16 ]. SGA was defined as the fetal birth weight ≤ 10th percentile according to local standards [ 1 ].…”