The Structure of the Lymph Node at Influence of Physical Loads and Infrasound

Abstract

The structure of the lymph nodes after exposure to physical loads and infrasound was studied. After the cessation of physical loads in the early stages of the study revealed a violation of the functional activity of lymph nodes with a tendency to their recovery. After 4 weeks after exposure to physical loads, the structure and function of the lymph nodes is fully restored and there is a slight activation of lymphopoiesis. After exposure to infrasound in the early stages of the study, there is a pronounced lymphostasis and compensatory increase in the functional activity оf В-zones of lymph nodes against the background of impaired migration of T-lymphocytes and inhibition of immunо-poiesis. After 4 weeks, against the background of persistent lymphostasis, there is a tendency to fibrous deformation of the stroma and exhaustion of the parenchyma of the nodes. Thus, the impact of intense noise, part of which is infrasound, has a more adverse effect on the lymph and immune–poietic functions of immune organs than the impact of intense physical loads in adapting to them.

Phytomodification Effects of Visceral Lymph Node Aging

“…The difference in structural response to aging depends mainly on the morphophysiological features of the lymphatic region [4]. Evidence of the regional principle of aging of peripheral lymphoid organs has been obtained, which confirms the introductory provisions of the lymphoid theory of aging [1,5,6] and the concept of the lymphatic region [4].…”

“…When aging, the intensity of changes varies in the lymph nodes of different regions. Age-induced changes affect cells and their microenvironment, compartments in the lymph node, and bioelement exchange, reducing its operability [3,6,[17][18][19][20] and reflecting the regional specificity of aging [4].…”

“…Most scientists note that tissue dehydration also comes with age [4][5][6]. There is no exception for lymph nodes either.…”

“…Many organs are susceptible to aging, and peripheral lymphoid organs are no exception. Lymphoid tissue involution reduces immune protection and interstitial drainage in the lymphatic region [4][5][6][7]. Destabilization of the lymphatic system increases the risk of age-induced organ pathology [1,8].…”

“…The lymph system, including lymph nodes, is vital to body fluid homeostasis. This requires additional study in aging [1,6]. Age changes in trace element balance [9,10] are accompanied by peripheral lymphoid organs disrupting the immune response mechanism.…”