The structure of cymbopogone, a novel triterpenoid from lemongrass

Crawford, Malcolm; Hanson, Svenja; Koker, Moustapha E. S.

doi:10.1016/s0040-4039(00)75085-4

Cited by 20 publications

(6 citation statements)

References 9 publications

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“…The major component of lipid class D (D10), exhibited and 13C NMR signals and a GC-MS fragmentation pattern which identified it as friedelin. Nine methyl signals (two as a doublet) correspond to the signals reported for the eight methyl groups on the friedelin molecule (Crawford et al 1975). The 13C spectral features of D10 were identical to a specimen prepared by Dr. N. Fisher from epifriedelinol.…”

Section: Resultsmentioning

confidence: 65%

Friedelin, the Major Component of Grapefruit Epicuticular Wax

Nordby¹,

McDonald²

1994

J. Agric. Food Chem.

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Section: Resultsmentioning

confidence: 65%

Friedelin, the Major Component of Grapefruit Epicuticular Wax

Nordby¹,

McDonald²

1994

J. Agric. Food Chem.

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“…Its chemical components like phenol and flavanoid substances were reported to show many in vitro and in vivo biological activities such as antioxidant, anti-inflammatory, and antimutagenic activities. [ 11 ] Apart from these biological activities, lemongrass essential oil has a wide range of antimicrobial effects such as anti-amebic, antifungal, antimycobacterial, and antibacterial against both gram-positive and gram-negative organisms. [ 10 ] At a concentration ≤2%, lemongrass essential oil could inhibit the growth of several kinds of microorganisms.…”

Section: Introductionmentioning

confidence: 99%

Lemongrass essential oil gel as a local drug delivery agent for the treatment of periodontitis

et al. 2013

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Background:It has been long recognized that periodontal diseases are infections of the periodontium, comprising the bacterial etiology, an immune response, and tissue destruction. Treatment strategies aiming primarily at suppressing or eliminating specific periodontal pathogens include adjunct use of local and systemic antibiotics as part of nonsurgical periodontal therapy. Unwanted side effects and resistance of microorganisms toward antibiotics due to their widespread use have modified the general perception about their efficacy. Research in phytosciences has revealed various medicinal plants offering a new choice of optional antimicrobial therapy. Cymbopogon citratus, Stapf. (lemongrass) is a popular medicinal plant. At a concentration ≤2%, lemongrass essential oil inhibits the growth of several kinds of microorganisms including periodontal pathogens, especially the reference strains Actinomyces naeslundii and Porphyromonas gingivalis, which were resistant to tetracycline hydrochloride.Aims:To evaluate the efficacy of locally delivered 2% lemongrass essential oil in gel form as an adjunct to scaling and root planing, as compared to scaling and root planing alone for the treatment of chronic periodontitis.Materials and Methods:2% Lemongrass essential oil gel was prepared and placed in moderate to deep periodontal pockets after scaling and root planing.Results:Statistically significant reduction in probing depth and gingival index and gain in relative attachment level were noted in the experimental group as compared to the control group at 1 and 3 months.Conclusion:Locally delivered 2% lemongrass essential oil gel offers a new choice of safe and effective adjunct to scaling and root planing in periodontal therapy.

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“…It can also act via terminating the chain reaction of lipid metabolism by donating hydrogen to free radical ( 31 ). Flavonoid, a chemical component of lemongrass oil has many biological activities, viz., antioxidant, anti-inflammatory, antimicrobial, antimutagenic and anti tumour ( 32 ). Therefore, its activity can evade oxidation reaction along with reducing hydroxyl radical, peroxyl radical and superoxide ( 33 ).…”

Section: Discussionmentioning

confidence: 99%