The Structure of Cascarosides A and B

Fairbairn, James; Friedmann, Carlotta; Simić, Svetislav D.

doi:10.1111/j.2042-7158.1963.tb11225.x

Cited by 7 publications

(2 citation statements)

References 2 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Aloinoside B was finally characterized as aloe-emodin-g-anthrone-1o-D-glUcoSyl-1 1 -mono-a-Lrhamnoside . Extracts of cascara bark yield four compounds which were shown to be O-glycosides of barbaloin or chrysaloin (Fairbairn & Simic, 1960;Fairbairn, Friedmann & Simic, 1963) (Fig. 5).…”

mentioning

confidence: 99%

The compounds in Aloë leaf exudates: a review

Reynolds

1985

Botanical Journal of the Linnean Society

110

View full text Add to dashboard Cite

The drug Bitter Aloes has been used for several thousands of years because of its purgative properties and later several species of the plant have been cultivated for horticultural interest. In addition, many more local therapeutic properties have been recorded. Research has been largely directed towards the physiologically active components during the 50s and 60s. Extensions to this work in the last decade have been made in Germany, Japan and South Africa. Compounds have been characterized from the dried exudate prepared for drug purposes and from a few species. A number of anthraquinones have been recognized both in the free state and as glycosides. Other compounds with phenolic groups include chromones and a phenyl‐pyranone. Chromatographic methods have been developed for recognizing some of these compounds and estimating the levels of those of pharmacological interest. Distribution of some of the compounds among a number of species is described showing that among some groups it has taxonomic significance. The biology of secretion and exudation from Aloë leaves remains largely unknown although fragmentary evidence points to interesting and potentially useful activity in some of the components.

show abstract

mentioning

confidence: 99%

The compounds in Aloë leaf exudates: a review

Reynolds

1985

Botanical Journal of the Linnean Society

110

View full text Add to dashboard Cite

show abstract

“…Glycosides containing a sugar moiety linked to the aglycone through a C-C bond require simultaneous oxidation and hydrolysis. Usually acidic ferric chloride solution is employed for the purpose (2,3).…”

mentioning

confidence: 99%

Anthraquinone Drugs II: Inadvertent Acetylation of Aloe-Emodin During Preparation of Aglycones From Crude Drugs–UV, IR, and NMR Spectra of the Products

Gyanchandani¹,

Nigam²

1969

Journal of Pharmaceutical Sciences

View full text Add to dashboard Cite

Trennung des Aloins in Diastereomere und deren Charakterisierung

Auterhoff

Graf

Eurisch

et al. 1980

Archiv der Pharmazie

View full text Add to dashboard Cite

Aloin wurde durch Hochdruckflüssigkeitschromatographie in Aloin A und Aloin B getrennt. Aloin A läßt sich aus Aloin auch durch mehrfache Kristallisation aus Methanol rein gewinnen. Die Aloine unterscheiden sich insbesondere durch ihre optischen Drehwerte und circulardichroitischen Effekte. Wie die Partialsynthese aus Anthronen und α‐Bromacetoglucose zeigte, ist in beiden Aloinen der Glucosylrest β‐ständig mit dem Aloeemodinanthron verbunden; C‐1′ des Glucosylrestes ist R‐konfiguriert. Aloin A und B unterscheiden sich durch die Konfiguration von C‐10 des Anthronrestes. Die Auswertung der 1H‐NMR‐Spektren macht für Aloin A die 10 R, 1′R‐Konfiguration wahrscheinlich, für das chemisch labilere Aloin B die 10 S,1′R‐Konfiguration.

show abstract

The Structure of Cascarosides A and B

Cited by 7 publications

References 2 publications

The compounds in Aloë leaf exudates: a review

The compounds in Aloë leaf exudates: a review

Anthraquinone Drugs II: Inadvertent Acetylation of Aloe-Emodin During Preparation of Aglycones From Crude Drugs–UV, IR, and NMR Spectra of the Products

Trennung des Aloins in Diastereomere und deren Charakterisierung

Contact Info

Product

Resources

About