The structure and bioactivities of Stemona alkaloids and alkaloids with [1,2-α] azepine nucleus (2009–2021)

Reductive Oxy-Nazarov Cyclization toward Expedient Construction of a Cyclopenta[1,2-b]pyrrolo[1,2-a]azepine Ring System: Formal Total Syntheses of Stemonamine and Cephalotaxine

“…The intriguing cyclopenta­[1,2- b ]-pyrrolo­[1,2- a ]­azepine ring skeleton is commonly found in bioactive stemonamine-type Stemona and Cephalotaxus alkaloids. Among the selected alkaloids shown in Figure , stemonamine 1 and stemonamide 2 from Stemona plants were used as traditional Chinese and Japanese folk medicine for curing respiratory diseases and infections .…”