The Structural Changes in Striped Muscle During Contraction

Jordan, H. E.

doi:10.1152/physrev.1933.13.3.301

Cited by 45 publications

(8 citation statements)

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“…With contraction, striated muscle changes its shape but maintains its volume almost perfectly. Consistent with this fact, the sarcomere of a myofibril thickens as it shortens (1), and also appears to maintain a constant volume. The striation changes which accompany changes in sarcomere length have been fitted to a sliding-filament model (2,3) which has formed the basis for a hypothesis on the mechanism of muscle contraction (4).…”

Section: Introductionmentioning

confidence: 56%

The Relationship Between Myofilament Packing Density and Sarcomere Length in Frog Striated Muscle

Brandt

López

Reuben

et al. 1967

The Journal of Cell Biology

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In cross-sections of single fibers from the frog semitendinosus muscle the number of thick myofilaments per unit area (packing density) is a direct function of the sarcomere length. Our data, derived from electron microscopic studies, fit well with other data derived from in vivo, low-angle X-ray diffraction studies of whole semitendinosus muscles. The data are consistent with the assumption that the sarcomere of a fibril maintains a constant volume during changes in sarcomere length. The myofilament lattice, therefore, expands as the sarcomere shortens. Since the distance between adjacent myofilaments is an inverse square root function of sarcomere length, the interaction of the thick and the thin myofilaments during sarcomere shortening may occur over distances which increase 70 A or more. The "expanding-sarcomere, sliding-filament" model of sarcomere shortening is discussed in terms of the current concepts of muscle architecture and contraction.

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Section: Introductionmentioning

confidence: 56%

The Relationship Between Myofilament Packing Density and Sarcomere Length in Frog Striated Muscle

Brandt

López

Reuben

et al. 1967

The Journal of Cell Biology

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“…It is this aspect of the question to which most of our results are relevant, but the experiments were originally planned in the hope of deciding a different point, namely, whether contraction bands are formed, and, if so, under what conditions. The formation of contraction bands, and the consequent reversal of striations, was seen by many observers during the second half of the 19th century (see review by Heidenhain, 1899); this was confirmed by some more recent workers (Jordan, 1933;Speidel, 1939), but denied by others (Hiirthle, 1909;Buchthal et al 1936). Even if the reality of these contraction bands was admitted on this evidence, there remained the question whether their formation was an accompaniment of 'activation', of tension development or of shortening; this distinction could not be made on the existing evidence, since only slow contractions, with more or less unlimited shortening, had been studied.…”

mentioning

confidence: 83%

Measurement of the striations of isolated muscle fibres with the interference microscope

Huxley¹,

Niedergerke²

1958

The Journal of Physiology

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“…Their explanation for this finding was that sarcomere lengths were not constant throughout the length of the muscle. These authors referred to the work of Jordon (1933) and Brandt et al (1967) who demonstrated that short sarcomeres, representing some degree of contraction, are thicker than the longer sarcomeres in the same fiber, and since the muscle was not rigidly constrained during freezing, it was possible that small focal or localized contractions may have occurred at various locations along the fiber. Consequently, if variations in sarcomere length within a fiber were random, it would not be expected that the diameter of adjacent fibers would alter in unison.…”

Section: Between Procedures (mentioning

confidence: 99%

Problems associated with the morphometric measurement of transverse skeletal muscle fibers: I. Analysis of frozen sections

Shorey

Cleland

1983

Anat. Rec.

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The aim of this study was to evaluate the effects of a number of reported procedures which precede freezing on the cross sectional area of skeletal muscle fibers. Probable sources of variation were recognised as: Within blocks, same animal, same procedure. Variability in the size of muscle fibers from area-based measurements was determined for the anterior head of the biceps femoris muscle of the rat. Fibers were measured within areas selected at random from sections taken from the same block of tissue. Variance within and between sections was subsequently established. Between blocks from rats having undergone the same procedure. Variability in the size of muscle fibers measured within areas selected at random from sections taken from different blocks of tissue within the same animal. Between rats, same or equivalent procedure. Fibers were measured from randomly selected areas within sections taken from blocks of tissue derived from different animals. The muscles were subjected to the same or equivalent treatment prior to freezing. Between procedures. Restraining muscles prior to and during freezing did not significantly affect the results except the procedure involving holding the muscle between two pairs of forceps. However, the variability was high within and between sections and blocks from the same muscle. It is postulated that the variability is of technical rather than biological origin and may be the result of small focal contractions which occur along the fibers during freezing.

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The Structural Changes in Striped Muscle During Contraction

Cited by 45 publications

References 0 publications

The Relationship Between Myofilament Packing Density and Sarcomere Length in Frog Striated Muscle

The Relationship Between Myofilament Packing Density and Sarcomere Length in Frog Striated Muscle

Measurement of the striations of isolated muscle fibres with the interference microscope

Problems associated with the morphometric measurement of transverse skeletal muscle fibers: I. Analysis of frozen sections

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