The strange case of metal coordination in disubstituted-biquinolines: competition between ligands and formation of a hybrid organic/inorganic Cu(II)/Cu(I) ternary cocrystal

Conjugation of a Silver-Based Coordination Polymer with Curcumin: A New Case of an Inorganic Polymeric Co-crystal

“…In addition, new categories of multicomponent crystals are currently under development. In particular, the rare polymeric co-crystals in which at least one component is a polymer are promising materials since the choice of a polymeric drug and/or co-former could represent an ingenious pharmaceutical strategy to modulate the stability, the solubility, and the release of poorly soluble drugs. − However, polymeric co-crystals as well as inorganic co-crystals have been infrequently obtained due to the fact that, in order to obtain a co-crystal, the starting materials should possess structural similarity, comparable potential energies, and almost identical crystallization kinetics. , Indeed, although a great number of organic co-crystals are known, few examples of co-crystals including a metal complex have been reported so far. − Metal complexes with their precise geometries hardly exhibit lattice packing forces and crystallization kinetics similar to small organic compounds. Many examples of inorganic co-crystals are actually composed of two parent metal complexes , or geometrical isomers of the same coordination compound …”