The Straining Forces of Bowel Function

Mitigating the Destructive Aspects of Drug-Induced Constipation On the Vascular System

“…The dosage of the laxative was adjusted to meet the fluctuating requirements of the patient and the effect of such a regimen on the essential pharmacology of the drug used was observed. The results of this phase of the study are presented in table 6.…”

“…Constipation is a common problem of patients forced to restrict their activities and becomes an even more important difficulty in those confined to bed, particularly when use of the bed pan is obligatory.5 The effect of the bed pan on the frequency and duration of straining was shown to be particularly adverse.s 6 Perhaps the most important influence in the development of constipation in these patients is the drugs used to treat the major disease. During the course of the survey, the panel of physicians was asked whether, in their experience, drug- induced constipation had necessitated the concurrent use of laxatives and 57 per cent of the group (124 physicians) reported this need.…”

Cardiovascular Response to Defecating Postures with and without Valsalva Maneuver in Healthy Individuals

“…6 There is a common agreement that VM has adverse effect on cardiovascular system and is one of the causative factors for defecation syncope and sudden death in elderly individuals. [7][8][9] The VM associated with the act of defecation/micturition may be considered as one of the triggering factor for cardiovascular incidence in compromised cardiovascular disease population. 10,11 Normal defecation consists of three components: Spontaneous phasic rectal contraction, relaxation of the anal canal, and straining (somatic component).…”