The storage stability of chitosan/tripolyphosphate nanoparticles in a phosphate buffer

Preparation and In Vitro Evaluation of Chitosan Nanoparticles Containing Diclofenac Using the Ion-Gelation Method

“…Their results indicated that the size of the nanoparticles decreased with increase of the solutions' pH. They suggested that CS/TPP nanoparticles are metastable nano-gels, and their structures are easily changed with different environmental conditions such as pH and ionic strength of the solutions (18). Chitosan is a polycation, which expands at lower pH values due to higher protonation and electrostatic repulsive interaction between polymer chains, and produces nanoparticles with larger particle size.…”

Preparation and optimization of Pickering emulsion stabilized by chitosan-tripolyphosphate nanoparticles for curcumin encapsulation

“…It is considered that CSeTPP NPs are formed mainly through the electrostatic interaction between positively charged CS and negatively charged TPP molecules. This interaction requires only mild conditions in terms of temperature and pH (Zhang, Oh, Allen, & Kumacheva, 2004) and the NPs size can be controlled by varying the CS: TPP ratio, pH and the molar mass of the CS (Hu et al, 2008;Tsai, Chen, Bai, & Chen, 2011). The physical cross-linking process between CS and TPP not only avoids the use of chemical crosslinking and emulsifying agents which are often toxic to organisms, but also prevents the possibility of damage to drugs, particularly biological agents (Berger et al, 2004).…”

Latent Fingerprint Enhancement Using Tripolyphosphate-Chitosan Microparticles

“…When freshly prepared, the diameters of the TPP-chitosan particles were in the range 1-1000 m (Figure 2) which is considerably larger than has been demonstrated in previous studies [4,[9][10][11][12][13][14][15] and may be explained in part by the molar mass and solubility of the chitosan. In so much as higher molecular weight chitosans produce larger particles [4,[15][16][17][18].…”

“…The use of TPP-chitosan in latent fingerprint enhancement was significantly affected by TPP : chitosan ratio, it was also expected that the storage temperature [4], concentration [18], molar mass [4,[15][16][17][18], and levels of aggregation, charge, and degree of deacetylation (DD) of chitosan will be of importance. Furthermore, it may be possible to form the microparticles directly on fingerprint in a 2-stage process.…”