The Steatocrit

Colombo, Carla; Maiavacca, Rita; Ronchi, M; Consalvo, Enza; Amoretti, M.; Giunta, Anna

doi:10.1097/00005176-198711000-00018

Cited by 40 publications

(4 citation statements)

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“…Fecal elastase-1 levels have a good correlation with fecal fat excretion, which was measured by employing the acid steatocrit test [34]. Th e steatocrit test used, due to its simple performance and noninvasiveness, is used in pediatric practice to monitor dietary fat malabsorption [37]. Th e present study has important limitation: there was a relatively small sample size.…”

Section: Discussionmentioning

confidence: 85%

Pancreatic exocrine disfunction in children with type 1 diabetes mellitus

Gorelov

Nijevitch²,

Malievsky³

et al. 2023

jour

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The aim of the present study was to evaluate exocrine pancreatic function in children with type 1 diabetes mellitus during the course of the disease.Fecal elastase varied between 24.4 and 169.6 μg /g (median 134.5 μg /g) in children with type 1 DM and concomitant PEI. Number of children with diarrhea was not significantly different between children with low pancreatic elastase levels and those with normal levels (43.0% versus 35.5%, p=0.359). The remainder of the children with type 1 DM had fecal elastase-1 levels between 201.4 and 810.5 μg /g stool (median 650.7 μg /g). Differences between the type 1 DM patients without PEI and the comparison group were not significant (p=0.112).Median daily fecal fat excretion in type 1 DM patients with PEI was 8.31 g/day (min-mах 7.81–9.21 g/day), which was significantly higher than in type 1 DM children without PEI (3.87 g/day; min-mах 2.97–6.33 g/day; р= 0.0003). There was no significant difference in daily fecal fat excretion between children with type 1 DM without signs of PEI and children in the control group (2.91 g/d; min-max: 2.31–5.74 g/d; р= 0.091).The results of this study demonstrate PEI in children with long-standing type 1 DM.Fecal elastase-1 concentration significantly correlates with duodenal exocrine elastase output. Fecal elastase-1 levels have a good correlation with fecal fat excretion, which was measured by employing the acid steatocrit test.

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Section: Discussionmentioning

confidence: 85%

Pancreatic exocrine disfunction in children with type 1 diabetes mellitus

Gorelov

Nijevitch²,

Malievsky³

et al. 2023

jour

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“…The steatocrit is a simple and rapid micromethod that can be repeated at short time intervals (3). It is inexpensive and not invasive (5). Some authors have reported it as a very satisfactory screening test (3‐5), but others have found it quite unreliable (6).…”

Section: Discussionmentioning

confidence: 99%

“…It is inexpensive and not invasive (5). Some authors have reported it as a very satisfactory screening test (3‐5), but others have found it quite unreliable (6). Our experience with the method has shown the steatocrit to often be normal in fecal samples with a very high chemically measured fecal fat content.…”

Section: Discussionmentioning

confidence: 99%

“…In 1981 Phuapradit introduced the steatocrit method as a new, simple, and easily repeatable method for measuring fecal fat content (3). Although several authors have reported this method to be satisfactory for the evaluation of steatorrhea (3‐5), some described it as quite unreliable (6). We have been using this method for years and have often found normal steatocrit values in patients who, when measured chemically, had steatorrhea with an increased fecal fat content.…”

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Improved Steatocrit Results Obtained by Acidification of Fecal Homogenates Are Due to Improved Fat Extraction

Tran,

Forget,

Van den Neucker

et al. 1996

J. pediatr. gastroenterol. nutr.

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SummaryConflicting results have been reported on the value of the steatocrit as a screening test for steatorrhea. We recently modified the test procedure by fecal acidification with the hope of improving fat extraction and consequently the sensitivity of the test. The aim of the present study was to ascertain whether or not fecal acidification led to improved fat extraction by comparing the fat content of both fatty and solid layers obtained by centrifugation of 12 acidified (acid steatocrit) and unacidified (classical steatocrit) steatorrheal stool samples. The fat content of fatty and solid layers was evaluated using the semiquantitative (+ = 1, + + = 2, + + + = 3) scoring system described by Drummey for the interpretation of the Sudan microscopic method for fecal fat. The fatty layers sum of scores for the 12 samples examined was 31 and 16 for the acid and classical steatocrit, respectively. The solid layers sum of scores for the 12 samples was 13 and 24 for the acid and classical steatocrit, respectively. Fat extraction from stool samples was significantly improved after fecal sample acidification (p < 0.005). Acid steatocrit results agreed better with chemically measured fecal fat than classical steatocrit results. We conclude that fecal acidification, by improving fat extraction, increases the reliability of the steatocrit method for the detection of steatorrhea.

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Cystic Fibrosis

Greening¹

2000

Crofton and Douglas's Respiratory Diseases

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The Steatocrit

Cited by 40 publications

References 0 publications

Pancreatic exocrine disfunction in children with type 1 diabetes mellitus

Pancreatic exocrine disfunction in children with type 1 diabetes mellitus

Improved Steatocrit Results Obtained by Acidification of Fecal Homogenates Are Due to Improved Fat Extraction

Cystic Fibrosis

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