The Status of the Complement-Fixation Test in Relation to the Cure of Syphilis

Relation of Natural Antisheep Hemolysin of Human Serums to Kolmer's Quantitative Complement-Fixation Test for Syphilis

“…2 The results reported by various and numerous workers with the quantitative complement-fixation method described by Kolmer3 have been such as to demonstrate for this technic a remarkable degree of delicacy and specificity, so much so that a considerable degree of reliance may be placed on positive reactions obtained with it as indicative of the presence of syphilitic reagin. Even if, because of the presence of large amounts of-antisheep hemolysin, weakly positive serums gave a false negative reaction, the abandonment of syphilis as a diagnostic possibility or the cessation of treatment or observation should not be allowed to rest on the sole basis of a single sérologie examination.…”