The Status of Hypertension Management in Japan in 2000.

Yamamoto, Yorihiro; Sonoyama, Kazuhiko; Matsubara, Koichi; Furuse, Masahiro; Yatsuhashi, Toru; Hamada, Toshihiro; Oginö, Kazuhíde; Igawa, Osamu; Hisatome, Ichiro; Shigemasa, Chiaki

doi:10.1291/hypres.25.717

Cited by 36 publications

(32 citation statements)

References 39 publications

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“…Although the percentage of patients using diuretics in the present study was higher than that found in previous reports from Japan (3)(4)(5), the prescription rate of diuretics (8.6%) among patients with a history of stroke still seems to be low. In the Perindopril Protection against Recurrent Stroke study (PROGRESS), it was shown that combination therapy with an ACE-inhibitor (perindopril) and a diuretic (indapamide) appeared to reduce the risk of stroke (8).…”

Section: Number Of Diuretic Prescriptions (N)contrasting

confidence: 91%

“…The percentage of patients using diuretics (9.3%) in the J-HOME study was higher than that (4.0-5.4%) found in previous studies (3)(4)(5), but was similar to that found (12.6%) in another recent study (6). This trend could be attributable to the impact of recently published, large-scale intervention trials, such as the ALLHAT study, which emphasized the clinical significance of diuretics (1,16,17).…”

Section: Discussioncontrasting

confidence: 66%

“…In Japan, it has been reported that the percentage of treated hypertensives being prescribed diuretics was only 4.0-5.4% for the period from 1999 to 2002 (3)(4)(5), but was 13.0-14.0% between 2003 and 2004 (6, 7). However, the dosages of diuretics used were not mentioned in these reports.…”

Section: Introductionmentioning

confidence: 99%

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Current Usage of Diuretics among Hypertensive Patients in Japan: The Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) Study

et al. 2006

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In the Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) study, we examined the current situation with respect to the prescription of diuretics, including the prevalence of diuretic treatment and the dosages used for patients with essential hypertension in primary care settings. Of the 3,400 hypertensive patients included in the study, 315 (9.3%) patients (mean age: 66.9 ± 10.4 years; males: 43.5%) were prescribed diuretics. Compared with patients who were not using diuretics, those who were using diuretics were more obese and had more complications. The most commonly prescribed diuretic among the 331 prescriptions in the 315 diuretic users was trichlormethiazide (44%), followed by indapamide (15%) and spironolactone (14%). Among patients being treated with diuretics, monotherapy was used in only 5% of patients; in the majority of patients combination therapy including diuretics (95%) was used. Relatively low dosages of diuretics were generally used. There was a difference between the actual dosages prescribed and those recommended by the Japanese Society of Hypertension (JSH) guidelines or the product information approved in Japan. Compared with previous estimates of the prevalence of diuretic use in hypertensives in Japan (4.0-5.4%), the rate in the J-HOME study (9.3%) was higher. This may be attributable at least in part

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Section: Number Of Diuretic Prescriptions (N)contrasting

confidence: 91%

Section: Discussioncontrasting

confidence: 66%

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Current Usage of Diuretics among Hypertensive Patients in Japan: The Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) Study

et al. 2006

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“…A lack of data regarding the use of antihyperuricemic medications might have led to underestimation of the prevalence of hyperuricemia. Because the frequency of diuretics used as antihypertensives is low in Japan, 38 the influence of diuretics on our results was most likely small. Third, information on menopause was not available for our female subjects.…”

Section: Discussionmentioning

confidence: 92%

Associations between serum uric acid levels and the incidence of hypertension and metabolic syndrome: a 4-year follow-up study of a large screened cohort in Okinawa, Japan

et al. 2014

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The purpose of this study was to examine the associations between serum uric acid (SUA) levels and the incidences of hypertension and metabolic syndrome (MetS) in a large screened cohort of Japanese men and women. We evaluated 4812 subjects (males, 2528; females, 2284; mean age, 47.5 years) who underwent health checkups between 2006 and 2010 and were free of hypertension and MetS in 2006. After 4 years, 618 (13%), 764 (16%) and 158 (3%) subjects developed hypertension, MetS and hypertension with MetS, respectively. Increased SUA levels were significantly and positively associated with the incidences of hypertension, MetS and hypertension with MetS. Compared with the first quartile of SUA levels, the odds ratios (95% confidence intervals) for the third and fourth quartiles, respectively, were as follows: 1.5 (1.1-2.1; P = 0.0128) and 1.8 (1.2-2.5; P = 0.0022) for hypertension, 1.3 (0.9-1.9; P = 0.1910) and 1.8 (1.2-2.7; P = 0.0039) for MetS and 2.7 (1.1-6.6; P = 0.0276) and 3.2 (1.3-8.0; P = 0.0115) for hypertension with MetS. In conclusion, increased SUA levels were significantly and independently associated with the incidences of hypertension and MetS in subjects without hypertension or MetS at baseline. Increased SUA levels might also be correlated with the incidence of hypertension with MetS.

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“…Thus, after taking into account the results of the Kyushu Lipid Intervention Study (KLIS) (15), the pravastatin anti-atherosclerotic trial in the elderly (PATE) (16), and the Japan Lipid Intervention Trial (J-LIT) (17), the Japan Atherosclerosis Society (JAS) Guidelines for Diagnosis and Treatment of Atherosclerotic Cardiovascular Diseases-which included new lipid management goalswere published in July 2002. Recently, we reported the current status of blood pressure management in hypertensive patients in Japan (18), and in this report, we have assessed the status of lipid management in the same population. The aim of this study was to clarify the current status of lipid management of hypertensive patients and to identify problems that warrant improvement.…”

Section: Introductionmentioning

confidence: 99%

Current Status of Lipid Management of Hypertensive Patients

et al. 2003

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The Status of Hypertension Management in Japan in 2000.

Abstract: To evaluate the current status of the management of hypertensive patients in Japan, we investigated 907 treated hypertensive patients (486 females and 421 males; mean age, 66.7 years) followed by cardiologists.

Cited by 36 publications

References 39 publications

Current Usage of Diuretics among Hypertensive Patients in Japan: The Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) Study

Current Usage of Diuretics among Hypertensive Patients in Japan: The Japan Home versus Office Blood Pressure Measurement Evaluation (J-HOME) Study

Associations between serum uric acid levels and the incidence of hypertension and metabolic syndrome: a 4-year follow-up study of a large screened cohort in Okinawa, Japan

Current Status of Lipid Management of Hypertensive Patients

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