The state of play of rodent models for the study of Clostridioides difficile infection
Anaïs Brosse,
Héloïse Coullon,
Claire Janoir
et al.
Abstract:Clostridioides difficile is the most common cause of nosocomial antibiotic-associated diarrhoea and is responsible for a spectrum of diseases characterized by high levels of recurrence and morbidity. In some cases, complications can lead to death. Currently, several types of animal models have been developed to study various aspects of C. difficile infection (CDI), such as colonization, virulence, transmission and recurrence. These models have also been used to test the role of environmental conditions, such a… Show more
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