The standardisation of uveitis nomenclature (<scp>SUN</scp>) project

Jabs, Douglas A.; McCluskey, Peter; Palestine, Alan G.; Thorne, Jennifer E.

doi:10.1111/ceo.14175

Cited by 7 publications

(3 citation statements)

References 67 publications

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“…Inflammation was examined at each follow-up appointment using a standard cell and flare grading scale. 7 At each visit, the cornea was assessed for edema, and the vitreous was assessed for floaters. A macular cube/thickness OCT scan was done at the 1-and 3-month visits.…”

Section: Methodsmentioning

confidence: 99%

Nd:YAG Laser Capsulotomy: Efficacy and Outcomes Performed by Optometrists

Lighthizer,

Johnson,

Holthaus

et al. 2023

Optom Vis Sci

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Significance An increasing number of optometrists are performing Nd:YAG laser capsulotomy procedures; however, there is limited published information on the outcomes of these procedures. Purpose This study aims to assess the efficacy and safety of capsulotomy procedures performed by optometrists. Methods Subjects diagnosed with posterior capsule opacification (PCO) causing reduced vision and subjective visual complaints were recruited for this study. A baseline examination was performed to ensure that the subjects met all the necessary criteria. The procedure was performed by a licensed Doctor of Optometry at six different clinics and each subject was monitored for visual outcome and any potential complications. Results Subjects’ Snellen visual acuity improved from an average of 20/40 to 20/23 (P < .001) with no complications of increased intraocular pressure, inflammation, visually significant lens pitting, macular edema, or retinal detachment. 77 of 78 subjects who responded to a post-procedure survey (99%) reported subjective improvement in vision after capsulotomy. Conclusions Based on the outcomes of this study, YAG laser capsulotomies are effective treatments to improve patient vision that can be safely and effectively performed by optometrists.

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Section: Methodsmentioning

confidence: 99%

Nd:YAG Laser Capsulotomy: Efficacy and Outcomes Performed by Optometrists

Lighthizer,

Johnson,

Holthaus

et al. 2023

Optom Vis Sci

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“…Anterior segments were evaluated with a slit-lamp examination. Anterior cells were graded according to the classification by Standard Uveitis Nomenclature as established (grade 1 [1–5 cells], 2 [6–15 cells], 3 [16–25 cells], 4 [26–50 cells], 5 [>50 cells]) 6 . Intraocular pressure was determined by using a contact tonometer (Goldmann).…”

Section: Methodsmentioning

confidence: 99%

“…Anterior cells were graded according to the classification by Standard Uveitis Nomenclature as established (grade 1 [1-5 cells], 2 [6-15 cells], 3 [16-25 cells], 4 [26-50 cells], 5 [>50 cells]). 6 Intraocular pressure was determined by using a contact tonometer (Goldmann). Indirect ophthalmoscopy was performed in all patients to evaluate the vitreous and posterior segments.…”

Section: Ophthalmology Outcomesmentioning

confidence: 99%

Factors Associated With Adverse Outcomes in Uveitis Related to Spondyloarthritis

et al. 2023

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BackgroundEvaluating the efficacy and refractoriness to treatment and determining factors associated with adverse outcomes in uveitis associated with spondylarthritis (SpA) are complicated by the lack of validated outcome measures.ObjectivesThe aims of this study were to develop an outcome score SpA-U in patients with uveitis associated with SpA and to determine factors associated with adverse outcomes in patients with uveitis under systemic treatment.MethodsThe outcome score SpA-U was defined by best-corrected visual acuity, anterior chamber inflammation, macular edema and inflammation of posterior chamber, global assessment, and refractoriness to treatment. Factors associated with adverse outcomes in uveitis were studied using linear regression. For categorical factors, marginal averages and their SEs are displayed together with linear regression coefficients with 95% confidence intervals. For continuous factors, averages and SDs are reported in addition to linear regression coefficients with 95% confidence interval. Two regression coefficients are reported for each variable: unadjusted and adjusted for age at diagnosis and sex.ResultsOne hundred ninety-seven uveitis outbreaks were included. Sixty-two uveitis outbreaks (31%) were classified as severe, 42 as moderate (21%), and 93 as mild (47%) based on the definition and construction of outcome score. The results of the linear regression model revealed that the uveitis activity was more severe in patients with smoking history (β = 0.34), axial and peripheral involvement (β = 0.43), Ankylosing Spondylitis Disease Activity Score >2.1 (β = 0.45), positive HLA-B27 (β = 0.29), female sex (β = 0.19), patients with C-reactive protein elevation (β = 0.002), and bilateral ocular involvement (β = 0.32). At the same time, shorter disease evolution (β = −0.02) was associated with less severe uveitis activity.ConclusionWe have determined factors associated with adverse outcomes in patients with uveitis associated with SpA by developing an outcome score SpA-U that integrates ocular inflammatory activity, visual acuity, global assessment, and refractoriness to treatment.

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