The stabilization of .alpha.- and .beta.-diimines: hexaammineruthenium(III), -osmium(III), and -platinum(IV) condensed with .alpha.- and .beta.-diketones

Recognition of DNA Base Mismatches by a Rhodium Intercalator

“…[Rh(bpy) 2 (chrysi)] 3+ was synthesized by condensation of [Rh(bpy) 2 (NH 3 ) 2 ](PF 6 ) 3 with 5,6-chrysenequinone by a method analogous to that developed by Sargeson and co-workers (see the Supporting Information). , The mismatch binding properties of the separated Δ- and Λ-enantiomers were then examined in DNA photocleavage experiments on a set of 17-mer oligonucleotides, each containing one DNA base mismatch (Figure ). At 10 μM DNA duplex concentration, photoinduced cleavage by the rhodium complex is not apparent at B-form sites.…”

Stereo- and regio-specificity in organic synthesis promoted by metal ions

“…Imines bound to some metal ions are activated to attack by nucleophiles (19,20) provided the donation from the metal d electrons to the empty Tr* orbitals of the imine is not substantial (21).…”

Unprecedented twofold intramolecular hydroamination in diam(m)ine-dicarboxylatodichloridoplatinum(iv) complexes – ethane-1,2-diaminevs.ammine ligands

“…8 To the best of our knowledge, only four reports were published, dealing with the reaction of am(m)ineplatinum complexes with ketones affording the corresponding ketimines. [9][10][11][12] In addition, an acetonimineplatinum(II) complex, obtained via reaction of coordinated acetone and monocoordinated ethane-1,2-diamine, was published. 13 However, coordinated amine ligands intramolecularly attacking CQC bonds in platinum(IV) complexes have not been described so far.…”