Abstract:VIII procoagulant activity (VIII:C) was estimated by a two-stage assay method, on 100 pre- and post-transfusion samples obtained from severe haemophiliacs receiving regular treatment with a variety of VIII concentrate preparations. Close and significant correlation (r = 0.97 P less than 0.01) was obtained between freshly tested samples and samples stored for one month at -35 degrees C. No significant difference between the two samples was demonstrated by Student's paired-t-test. Forty-nine of the stored sample… Show more
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