The Spiraling Case of a Yellow Chef: Isolated Hyperbilirubinemia

Jiang, Karen; Bazarbashi, Ahmad Najdat; Dahdal, Sami; Voiculescu, Adina; Khalaf, Natalia

doi:10.1155/2018/5876718

Cited by 4 publications

(3 citation statements)

References 16 publications

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“…10,11 Leptospirosis presents with a conjugated hyperbilirubinaemia out of proportion to derangements in the liver enzyme profile as noticed in our patient. 12 In contrast, transaminitis is usually more prominent in the viral hepatitides. Imaging to exclude hepatic duct obstruction is appropriate in any patient with jaundice.…”

Section: Discussionmentioning

confidence: 99%

Deeply jaundiced: Not so surgical after all

du Plessis,

Lahri,

Somers

et al. 2023

Southern African Journal of Infectious Diseases

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Leptospirosis is an under-recognised disease in sub-Saharan Africa and the diagnosis requires a high index of suspicion. This case report highlights the protean manifestations of leptospirosis. Leptospirosis should be considered in any patient presenting with fever and jaundice, especially when there has been a history of occupational or recreational exposure to water, soil or rodents.Contribution: This case report describes a typical case of leptospirosis, which often presents as a diagnostic dilemma.

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Section: Discussionmentioning

confidence: 99%

Deeply jaundiced: Not so surgical after all

du Plessis,

Lahri,

Somers

et al. 2023

Southern African Journal of Infectious Diseases

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“…Most cases are either asymptomatic, or mild and self-limited, with less than 10% of cases progressing to severe illness with multiorgan failure. Common symptoms include fever, rigors, myalgias, headaches, conjunctival suffusion, non-productive cough, nausea, vomiting, and diarrhea [5]. Weil's Syndrome classically refers to renal and liver failure with jaundice.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Leptospirosis-Induced Liver Injury in an Urban Setting

Ahmed¹,

Subhan²,

Jasbir³

2022

J Clin Gastroenterol Treat

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and sheep. Rodents are the most important reservoirs, and once infected, they harbor and shed the pathogen through their urine. Human infection occurs when animal urine or contaminated water or soil comes in contact with mucous membranes, conjunctivae, or skin lacerations [2].On average, clinical manifestations of leptospirosis start after a 10-day incubation period. The infection varies from mild and self-limited illness in most cases, to a severe and potentially fatal disease. Symptoms are non-specific and include a wide range of different system involvement including gastrointestinal, respiratory, musculoskeletal, hepatic, and genitourinary systems. Case PresentationA 50-year-old African American man presented to the emergency department of a New York City hospital with a chief compliant of bilateral leg weakness. Patient said that one week prior to presentation, he had sudden onset of abdominal cramps, nausea, multiple episodes of non-bloody, non-bilious vomiting, and watery diarrhea, which all lasted for a few days. Patient attributed his gastrointestinal symptoms to street food he ate prior to the onset of his illness. His condition deteriorated, and he developed subjective fevers, chills, and severe muscle aches, mainly in his legs. Patient's muscle pain progressively worsened, to the point where he felt his legs became weak, causing difficulty walking, so he decided to seek medical attention. He denied any recent travel, sick contacts, alcohol use, use of over the

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“…During the hospital course, the patient responded well to therapy with rapid resolution of fever and improvement in AST, ALT, and kidney function; however, bilirubin continued to increase after initiation of antibiotics. This phenomenon is commonly seen in leptospirosis and should not be a worrying sign [ 14 , 15 ]. Electrolyte abnormalities seen in our patient (hypokalemia, hypomagnesemia) and prolonged myalgia are also common in leptospirosis [ 16 , 17 ], and physicians should check for those abnormalities and replete if necessary.…”

Section: Discussionmentioning

confidence: 99%

Weil’s Disease in an HIV-Infected Patient

Nguyen¹,

Chaparala²,

Morel³

et al. 2021

Cureus

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Leptospirosis is a zoonosis caused by the spirochete Leptospira . Most cases of leptospirosis are mild to moderate and self-limited. The course of disease, however, may be complicated by multiorgan dysfunction with liver and kidney failure causing Weil’s disease. Leptospirosis is also rare among HIV-infected patients. We report a case of an HIV-infected patient with Weil’s disease.

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The Spiraling Case of a Yellow Chef: Isolated Hyperbilirubinemia

Cited by 4 publications

References 16 publications

Deeply jaundiced: Not so surgical after all

Deeply jaundiced: Not so surgical after all

A Rare Case of Leptospirosis-Induced Liver Injury in an Urban Setting

Weil’s Disease in an HIV-Infected Patient

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