The Sphenoid Sinus

Hong, Seung Ho; Kim, Sung‐Dong; Roh, Hwan‐Jung; Cho, Kyu‐Sup

doi:10.1097/scs.0000000000000891

Cited by 6 publications

(2 citation statements)

References 7 publications

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“…Blastomas of the olfactory nerve and paragangliomas are of neuroectodermal origin and develop from the olfactory membrane or head and neck paraganglia 302 . According to the WHO classification, neuroendocrine tumors are considered as grade I neoplasms (formerly known as low-grade neuroendocrine tumors or typical carcinoid), grade II neoplasms (formerly called intermediary neuroendocrine tumor or atypical carcinoid), and grade III neoplasms, small-cell carcinoma (formerly called high-grade neuroendocrine tumor or small-cell carcinoma) as well as grade III neoplasms, large-cell carcinoma (formerly known as high-grade neuroendocrine tumor or large-cell neuroendocrine carcinoma) 303 .…”

Section: Rare Diseases Of the Nose The Paranasal Sinuses And The Snterior Skull Basementioning

confidence: 99%

“…They have a highly infiltrative growth behavior with frequent perineural and lymphovascular infiltration. Sinonasal neuroendocrine small-cell and large-cell carcinomas have a cytokeratin expression which allows differentiation for example with regard to olfactory neuroblastomas 303 .…”

Section: Rare Diseases Of the Nose The Paranasal Sinuses And The Snterior Skull Basementioning

confidence: 99%

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Seltene Erkrankungen der Nase, der Nasennebenhöhlen und der vorderen Schädelbasis

Sommer

2021

Laryngorhinootologie

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ZusammenfassungSeltene Erkrankungen der Nase, der Nasennebenhöhlen und der vorderen Schädelbasis stellen aufgrund der niedrigen Inzidenz und den daraus resultierend eingeschränkten diagnostischen Kriterien sowie therapeutischen Optionen eine Herausforderung dar. Der Schwellenwert, ab dem eine Erkrankung als selten zu werten ist, liegt bei höchstens 5 Betroffenen pro 10 000 Personen. Innerhalb dieser Erkrankungen gibt es allerdings extreme Schwankungen. So gehören einige seltene Erkrankungen, wie z.B. das invertierte Papillom, zu den regelmäßig diagnostizierten und therapierten Krankheitsbildern einer größeren Klinik für Hals-Nasen-Ohrenheilkunde. Andererseits liegen bei anderen seltenen Erkrankungen und Fehlbildungen weltweit deutlich unter 100 Fallberichte vor, was die Notwendigkeit einer Bündelung der verfügbaren Erfahrung zu Diagnostik und Therapie unterstreicht.Die vorliegende Arbeit gibt eine Übersicht zu seltenen Erkrankungen der Nase, der Nasennebenhöhlen und der vorderen Schädelbasis aus den übergeordneten Bereichen Erkrankungen / Syndrome des olfaktorischen Systems, Fehlbildungen der Nase und Nasennebenhöhlen, Belüftungs- und Funktionsstörungen sowie benigne und maligne Tumore. Die Einordnung sowie Angaben zu Diagnostik und Therapiemöglichkeiten wurden unter Berücksichtigung der aktuellen Literatur erstellt.

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Section: Rare Diseases Of the Nose The Paranasal Sinuses And The Snterior Skull Basementioning

confidence: 99%

Section: Rare Diseases Of the Nose The Paranasal Sinuses And The Snterior Skull Basementioning

confidence: 99%

Seltene Erkrankungen der Nase, der Nasennebenhöhlen und der vorderen Schädelbasis

Sommer

2021

Laryngorhinootologie

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Meta-analysis of 701 published cases of sinonasal neuroendocrine carcinoma: The importance of differentiation grade in determining treatment strategy

et al. 2016

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The aim of this meta-analysis was to provide treatment guidelines for sinonasal neuroendocrine carcinoma (SNC) by combining all available data in the literature. A literature search for all studies concerning SNC was performed against the MEDLINE and EMBASE databases. Available clinical data was normalized, pooled, and statistically analyzed. A total of 701 cases of SNC were available for analysis, comprising 127 well or moderately differentiated sinonasal neuroendocrine carcinomas (SNEC), 459 sinonasal undifferentiated carcinoma (SNUC) and 115 sinonasal small cell carcinoma (SmCC). Tumor type was the most important predictor of survival, with a 5-year disease-specific survival (DSS) of 70.2% for SNEC, 35.9% for SNUC and 46.1% for SmCC. Tumor stage on presentation was of limited value in predicting survival or response to treatment. Overall, the application of surgery yielded significantly better results (5-year DSS 52.2% versus 30.1%, p<0.001). In SNUC, radiotherapy was a beneficial supplement to surgery (5-year DSS 54.7% versus 15.7%, p=0.027), while radiotherapy as monotherapy performed poorly (5-year DSS 17.9%). Chemotherapy did not appear to contribute to survival. Based on these findings, we can conclude that the most important predictors of survival in SNC are differentiation grade and the associated choice of treatment modality. In contrast to other head and neck cancers, tumor staging appears of limited value in predicting survival or deciding on a treatment strategy. Surgery should be the cornerstone of treatment, supplemented by radiotherapy in poorly differentiated subtypes (SNUC, SmCC). Chemotherapy does not appear to contribute to survival.

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Primary skull base neuroendocrine carcinoma—a case report and review of literature

Joshi

Thombare

Verma

et al. 2020

Radiology Case Reports

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The Sphenoid Sinus

Cited by 6 publications

References 7 publications

Seltene Erkrankungen der Nase, der Nasennebenhöhlen und der vorderen Schädelbasis

Seltene Erkrankungen der Nase, der Nasennebenhöhlen und der vorderen Schädelbasis

Meta-analysis of 701 published cases of sinonasal neuroendocrine carcinoma: The importance of differentiation grade in determining treatment strategy

Primary skull base neuroendocrine carcinoma—a case report and review of literature

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