The spectrum of oculocutaneous disease

Day, Antoinette; Abramson, Amanda; Patel, Mahir; Warren, Richard B; Menter, M. Alan

doi:10.1016/j.jaad.2013.12.019

Cited by 10 publications

(7 citation statements)

References 90 publications

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“…Stevens-Johnson syndrome (SJS) and toxic epidermaly necrolysis (TEN) are rare potentially fatal severe cutaneous adverse reactions characterized by extensive epidermal detachment and mucocutaneous involvement (Supplement Table 5, http:// links.lww.com/MOP/A66) [46 && ]. They are almost always drug-related with occasional infectious etiology [14,42]. In children, antibiotics, anticonvulsants, and nonsteroidal anti-inflammatory drugs are the most common inciting drugs [42,43,44].…”

Section: Stevens-johnson Syndromementioning

confidence: 99%

“…The most common ocular complications include conjunctivitis, episcleritis, corneal erosions/ulcerations, and symblepharon. These may lead to permanent visual deficits and sicca-like symptoms [14,47]. Due to the high propensity for ocular involvement, ophthalmologic consultation is mandatory in SJS/TEN.…”

Section: Stevens-johnson Syndromementioning

confidence: 99%

“…Due to the high propensity for ocular involvement, ophthalmologic consultation is mandatory in SJS/TEN. Treatment options include preservative-free lubricating eye drops, amniotic membrane transplantation, and symblepharon rings [14].…”

Section: Stevens-johnson Syndromementioning

confidence: 99%

“…Limited reviews on the association between cutaneous dermatoses and ocular disease exist in the pediatric literature. The number of oculocutaneous associations can be broadly classified into four etiologic categories: infectious, inflammatory, genetic, and medication/nutrition induced [8,14]. This review is designed to provide the pediatric practitioner a vignette-based high-level overview of both common and sight threatening associations that should prompt consideration for ophthalmology consultation.…”

Section: Introductionmentioning

confidence: 99%

“…Conditions were selected based on relevance, relative urgency, and recent advances in their etiologic/therapeutic understanding. A more detailed evaluation of associations can be found in the online supplementary material of this article (Supplementary Tables 1-3, http://links.lww.com/MOP/A66) [8,14,18,29,30]. An overview of ocular anatomy and associated disease states is included (Fig.…”

Section: Introductionmentioning

confidence: 99%

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The eyes have it: when skin findings prompt referral to ophthalmology

Dunn¹,

Foss²,

Kumar

2022

Current Opinion in Pediatrics

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Purpose of reviewCo-presentation of ocular and cutaneous conditions is common and prompt recognition of known associations may be imperative to sight-saving intervention. There are currently limited reviews in the pediatric literature addressing comorbid ocular and dermatologic presentations. Recent diagnostic and therapeutic advances have drastically altered the prognostic landscape for several disease states when recognition and referral are timely. The aim of this report is to examine important oculocutaneous disease associations with emphasis on management of ocular complications and appropriate referral practices to ophthalmology specialists. Recent findingsOculocutaneous associations can be broadly classified into four etiologic categories: infectious, inflammatory, genetic, and medication/nutrition induced pathology. Several conditions in all four categories have had recent advances in their etiologic understanding, diagnostic evaluation, and therapeutic approach. Thematically, these advances highlight increasing disease prevalence of certain conditions, previously unrecognized pediatric relevance of others, updated diagnostic criteria, and newer categories of iatrogenic illness induced by advances in medical therapy.

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