The spectrum of liver disease in systemic lupus erythematosus

Runyon, Bruce A.; LaBrecque, Douglas R.; Anuras, Sinn

doi:10.1016/0002-9343(80)90378-2

Cited by 235 publications

(71 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The high ferritin level suggested adult Still's disease, but signs such as skin lesions and arthralgia were not seen in the present case (20). Other collagen diseases which cause abnormal liver function tests were also unlikely since various autoantibodies and p-and CANCAwere negative (21,22). In the present case, lymph node swelling and hepatosplenomegaly were recognized in the prepulseless stage ofTakayasu' s arteritis.…”

Section: Discussionmentioning

confidence: 47%

Takayasu's Arteritis in Prepulseless Stage Manifesting Lymph Node Swelling and Hepatosplenomegaly.

et al. 1995

View full text Add to dashboard Cite

A 17-year-old male had fever of unknown origin (FUO) for 3 months with positive c-reactive protein, lymph node swelling, and hepatosplenomegaly. Biopsy specimens of the liver and lymph node disclosed nonspecific inflammation. Lymphnode swelling and hepatosplenomegaly subsided gradually, while vascular murmurand pulselessness appeared. Computerized tomography and magnetic resonance imaging showed thickened arterial wall, while angiography disclosed arterial narrowing. From these findings he was diagnosed to have Takayasu's arteritis. The therapy with prednisolone was effective. Takayasu's arteritis is rarely manifested by hepatosplenomegaly and lymphadenopathy in its prepulseless stage. (Internal Medicine 34: 455-459, 1995)

show abstract

Section: Discussionmentioning

confidence: 47%

Takayasu's Arteritis in Prepulseless Stage Manifesting Lymph Node Swelling and Hepatosplenomegaly.

et al. 1995

View full text Add to dashboard Cite

show abstract

“…The characteristic h1srolog1<. feature of autoimmune CAH 1s :1u1ve piecemeal necrosis of pcriporcal hcpacocytes (3,20). The two patients presented in Autoimmune CAH and PSC this rcron possessed many of l he nbove features.…”

Section: Discussionmentioning

confidence: 97%

Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females

Minuk

Sutherland

Pappas

et al. 1988

Canadian Journal of Gastroenterology

View full text Add to dashboard Cite

Autoimmune chron ic active hepatitis (CAH) and primary sderosing cholangitis (PSC) arc chronic diseases of the hepatobiliary system that have many cli nica l, immunologic and genetic features in commo n. Despite these similarities, there are few reports of the two diseases coexisting. Two young women with clinical, biochemical, serologic, radiologic and histologic findings compatible with both autoimmune CAH and PSC are described. The observation that there may be a striking overlap in the featu res of these two diseases and recent improvements in diagnostic imaging of the biliary tract suggest that the association of these two diseases in the same individual may be more common than is presently appreciated. Can J Gastroentero l 1988; 2(1): 22-27

show abstract

“…However, this cause was related to the activity of lupus in 8% of the cases,3 and the majority of biochemical abnormalities seen in these studies were usually secondary to other causes such as drug-induced liver dysfunction, alcohol, liver congestion from congestive heart failure, infection or metabolic disturbances. Hepatomegaly (39% to 42%) and jaundice (24%) were often seen at the onset of liver disease 12. Various forms of hepatic pathology related to SLE have been described, and they include fatty liver,24 portal inflammation,2 chronic active hepatitis,12 chronic persistent hepatitis,14 cirrhosis,1 cholestasis,14 hepatic necrosis associated with antiphospholipid antibody syndrome,5 granulomatous hepatitis,1 non-specific reactive hepatitis,4 nodular regenerative hyperplasia,4 hepatic infarction4 and arteritis 467…”

Section: Discussionmentioning

confidence: 99%

Hepatic vasculitis mimicking liver abscesses in a patient with systemic lupus erythematosus

Alanazi

Alqahtani

Duraihim

et al. 2009

Annals of Saudi Medicine

View full text Add to dashboard Cite

Clinical and radiological liver diseases are uncommon in patients with systemic lupus erythematosus (SLE). We report a 29-year-old female with SLE who presented with right upper quadrant abdominal pain, thrombocytopenia, elevated liver enzymes and multiple hypodense lesions in the liver on a computed tomography (CT) study that mimicked multiple liver abscesses. A liver biopsy showed mild chronic inflammation. Culture results were negative. With steroid therapy the patient improved clinically, the platelet count returned to the normal range and the multiple liver lesions disappeared radiologicaly. This patient represents a rare case of SLE that had hepatic vasculitis mimicking multiple liver abscesses.

show abstract

The spectrum of liver disease in systemic lupus erythematosus

Cited by 235 publications

References 22 publications

Takayasu's Arteritis in Prepulseless Stage Manifesting Lymph Node Swelling and Hepatosplenomegaly.

Takayasu's Arteritis in Prepulseless Stage Manifesting Lymph Node Swelling and Hepatosplenomegaly.

Autoimmune Chronic Active Hepatitis (Lupoid Hepatitis) and Primary Sclerosing Cholangitis in Two Young Adult Females

Hepatic vasculitis mimicking liver abscesses in a patient with systemic lupus erythematosus

Contact Info

Product

Resources

About