The spectrum of benign and malignant etiologies of cervical node calcification.

Unilateral Aplasia of the Submandibular Gland with Multiple Calcified Cervical Lymph Nodes: A Case Report and Review of the Litarutre

“…In a retrospective study, Eisenkraft and Som [26] monitored 2,300 neck-region CT scans and found that the prevalence of nodal calcifications was 1%. They are mostly associated with benign conditions, such as tuberculosis, histoplasmosis, sinus histiocytosis, actinomycosis, hemangioma phleboliths, and systemic or localized amyloidosis [27][28][29][30][33][34][35][36][37][38].…”

“…They are mostly associated with benign conditions, such as tuberculosis, histoplasmosis, sinus histiocytosis, actinomycosis, hemangioma phleboliths, and systemic or localized amyloidosis [27][28][29][30][33][34][35][36][37][38]. Although tuberculosis is commonly thought to be causative, calcification during cervical adenopathy appears to be uncommon in tuberculosis [26]. Baskota et al [35] reported that in patients with tuberculous cervical lympadenitis, the majority of the nodes are unilateral; of these, only one group of lymph nodes is usually involved.…”

“…Identification of soft tissue calcifications is difficult when relying on panoramic or lateral oblique radiographs alone. Although CT is an excellent imaging approach for revealing calcified lymph nodes, it does not allow for differentiation between benign and malignant lesions [26]. Therefore, biopsy is obligatory in almost all cases for diagnostic purposes.…”

“…Nodal calcifications in the neck are uncommon, occuring in only 1% of enlarged nodes [26]. They are mostly associated with benign inflammatory or infectious diseases [26][27][28][29][30].…”

“…They are mostly associated with benign inflammatory or infectious diseases [26][27][28][29][30]. Less frequently, this condition may be associated with malignant diseases [31,32].…”