The Solitary Pulmonary Nodule

Winer-Muram, Helen T.

doi:10.1148/radiol.2391050343

Cited by 297 publications

(264 citation statements)

References 98 publications

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“…Tüm akciğer grafilerinin %0,09-7'sinde SPN'ye rastlanmaktadır. 2,10,11 Akciğer kanseri nedeni ile yapılan BT taramalarında %8-51 oranında saptanmıştır. 4 SPN saptandığında en az invaziv yöntemle benign-malign ayrımı yapıl-maya çalışılmalıdır.…”

Section: Discussionunclassified

“…SPN'de etiyolojik spektrum hamartom gibi benign patolojilerden, ölümcül olabilen akciğer kanserine kadar geniş bir patoloji grubunu içermektedir. [1][2][3][4]6,10,11 Her ne kadar pulmoner nodül-lerin çoğu benign olsa da kanser tanısını dışlamak iki-üç yıllık bir zaman gerektirebilmektedir. Çalış-malarda, 50 yaş üstünde sigara içen ve nodül izlemi olan hastalarda çalışmamızla paralel olarak %1-1,5 oranında kanser gelişmektedir.…”

Section: Discussionunclassified

“…Sigara, pulmoner nodül etiyolojisindeki akciğer kanserinin iyi bilinen bir nedeni olup, aynı zamanda mevcut nodülün de malignite riskini artırmaktadır. [2][3][4][5] Akciğer kanseri ile sigara arasındaki ilişki pek çok çalışma ile gösterilmiştir. Saptanan nodüllerin malign olma ihtimali sigara varlığında artmaktadır.…”

Section: Pulmoner Nodül İzlemi Yapılan Hastalarınunclassified

“…Saptanan nodüllerin malign olma ihtimali sigara varlığında artmaktadır. 2,3 Akciğer kanseri riskinin yüksek olduğu düşünülen nodüller, algoritmalara uygun şe-kilde, radyolojik olarak takip edilmektedir. 5 Pulmoner nodül ile izlem altında olan hastaların sigarayı bırakmasu için ilk yapılan hekim önerisidir.…”

Section: Pulmoner Nodül İzlemi Yapılan Hastalarınunclassified

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Changes in Smoking Behavior of Patients with Pulmonary Nodule Follow-up

Üzer¹,

Özbudak²

2017

Turkiye Klinikleri Arch Lung

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Section: Discussionunclassified

Section: Pulmoner Nodül İzlemi Yapılan Hastalarınunclassified

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Changes in Smoking Behavior of Patients with Pulmonary Nodule Follow-up

Üzer¹,

Özbudak²

2017

Turkiye Klinikleri Arch Lung

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“…Controversy regarding its use is based on: (a) the falsenegative rate, which is as high as 29% [17] and approaching 60% among patients with nonspecific benign cytological findings [18]; (b) an incidence of pneumothorax of up to 30%, although only a minority of patients require further treatment [17][18][19][20][21][22] (chest tube in 5%-7% of cases developing pneumothorax); and (c) philosophically, many physicians consider the technique as superfluous and expensive and as an intermediate step with potential morbidity and only a small impact on definitive treatment [23][24][25].…”

Section: Diagnosis Of Indeterminate Pulmonary Nodulesmentioning

confidence: 99%

Indications and Developments of Video-Assisted Thoracic Surgery in the Treatment of Lung Cancer

Solli

Spaggiari

2007

The Oncologist

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After completing this course, the reader will be able to:1. Discuss the role of thoracoscopy in the evaluation of pulmonary nodules and pleural effusion.2. Describe the role of thoracoscopy in the staging of lung cancer.3. Discuss the role of thoracoscopy in surgical resection of early-stage lung cancer.Access and take the CME test online and receive 1 AMA PRA Category 1 Credit ™ at CME.TheOncologist.com CME CME ABSTRACTThe term video-assisted thoracic surgery (VATS) is used to describe a modern minimally invasive surgical technique that nowadays represents a valid alternative to open procedures (i.e., thoracotomy) for many chest diseases. The VATS approach is presently used in many intrathoracic disorders, but while well established in benign chest disease, its role continues to evolve regarding the management of lung cancer. It is currently considered for the evaluation and treatment of suspected (or known) pleural effusion and in the diagnosis of indeterminate pulmonary nodules, and it has a complementary role to standard cervical mediastinoscopy in the invasive staging of mediastinal lymph nodes. It has also become an accepted approach for resection of peripheral early-stage lung cancer (stage I) in many centers worldwide and considerable experience has been accumulated in respect to this field, but absolute indications have yet to be firmly defined. This paper reviews indications and current data regarding minimally invasive approaches for the staging and treatment of lung cancer.

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Noninvasive diagnosis of solitary pulmonary lesions in cancer patients based on 2‐fluoro‐2‐deoxy‐D‐glucose avidity on positron emission tomography/computed tomography

Bar‐Shalom

Kagna

Israel

et al. 2008

Cancer

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BACKGROUND.2‐Fluoro‐2‐deoxy‐D‐glucose (FDG) imaging is highly accurate for assessing solitary pulmonary nodules (SPNs) in patients without known malignancy. In the current study, the authors evaluated FDG‐positron emission tomography/computed tomography (PET/CT) for the characterization of SPN in cancer patients.METHODS.FDG‐PET/CT was performed in 56 cancer patients to evaluate SPNs that measured 15 ± 8 mm in greatest dimension. The diagnosis was confirmed by histology (n = 34 patients), or by CT or clinical follow‐up (n = 22 patients). The performance of PET/CT was calculated for visual and semiquantitative assessment and was related to SPN size, location, histology, and time after initial cancer diagnosis.RESULTS.Malignancy was diagnosed in 27 of 56 SPNs (48%; 18 second primary tumors and 9 metastases). There were 26 true‐positive PET/CT studies (17 second primaries and 9 metastases), 5 false‐positive studies, 24 true‐negative studies, and 1 false‐negative study. The sensitivity of PET/CT for diagnosing malignant SPN in patients with cancer was significantly greater for visual analysis than for semiquantitative analysis (96% vs 89%, respectively; P < .05). Specificity and accuracy were similar for both methods (83% and 89% vs 93% and 91%, respectively). The presence of low‐intensity FDG uptake increased the detection rate of malignancy from 4% in non‐FDG–avid SPNs to 40%, mainly in second primary tumors. False‐positive results were more frequent with lower than mediastinal uptake versus higher than mediastinal uptake (3 of 5 SPNs vs 2 of 26 SPNs, respectively; P < .01) and in SPNs >10 mm.CONCLUSIONS.FDG imaging was highly accurate for the diagnosis of malignant SPNs in patients with cancer, similar to the general population. The presence of any FDG avidity had significantly greater sensitivity than semiquantitative analysis. The current results indicated that lower than mediastinal uptake should be explored cautiously, particularly for second primary tumors, whereas no FDG avidity was a better predictor of SPN benignity than very low uptake. Cancer 2008. © 2008 American Cancer Society.

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The Solitary Pulmonary Nodule

Cited by 297 publications

References 98 publications

Changes in Smoking Behavior of Patients with Pulmonary Nodule Follow-up

Changes in Smoking Behavior of Patients with Pulmonary Nodule Follow-up

Indications and Developments of Video-Assisted Thoracic Surgery in the Treatment of Lung Cancer

Noninvasive diagnosis of solitary pulmonary lesions in cancer patients based on 2‐fluoro‐2‐deoxy‐D‐glucose avidity on positron emission tomography/computed tomography

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